Resumo

ASQUINO, Natalia et al. Bone resorption in periodontal disease: the role of RANK, RANKL and OPG. A literature review. Odontoestomatología [online]. 2022, vol.24, n.40, e316.  Epub 01-Dez-2022. ISSN 0797-0374.  https://doi.org/10.22592/ode2022n40e316.

Periodontitis is one of the most prevalent oral diseases. The study of its pathogenesis has significantly advanced in recent years. However, the details of the mechanisms involved in bone resorption are not clear yet. RANK, RANKL, and OPG are proteins that have a known role in other bone tissue diseases. This paper reviews the evidence of their potential participation in the pathogenesis of periodontal disease. More evidence is needed to understand the relationship between RANK, RANKL, OPG, and bone resorption in periodontitis.

Palavras-chave : periodontal disease; RANK; RANKL; OPG.

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