Resumo

VALVERDE, Marcelo et al. Usefulness of the Type B Natriuretic Peptides in Heart Failure. Arch. Med Int [online]. 2009, vol.31, n.2-3, pp.61-68. ISSN 0250-3816.

Chronic Heart Failure (CHF) is arising as a real epidemic on the XXI century. Their high incidence and prevalence, and the notable impact on population morbidity and mortality, generates continuous growths of its costs. By the fact it is clear that it represents a really public health problem, in which opportunely interventions must be taken. Despite the notable advances made on the knowledge of this disease in the last decades, it still represents a real challenge for clinicians when diagnosis has to be made, and on the management of guidelines for follow-up, therapeutic adjustments, and prognosis for a particular patient. All this issues are useful for the decision-making process in clinical practice. Recently, based on the “Neurohumoral profile” of CHF, the neuroendocrine mediators have been studied extensively. A kind of these markers, the Natriuretic Peptides, and particularly B-Type Natriuretic Peptides (BNP), has been identified as the more applicable ones in clinical practice. On this paper the definition, biological properties and usefulness of BNP are reviewed, with the objective of delineating the future development of practice guidelines and integrating them on disease management.

Palavras-chave : Neurohumoral Markers; Natriuretic Peptides; Chronic Heart Failure.

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