<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1688-0420</journal-id>
<journal-title><![CDATA[Revista Uruguaya de Cardiología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev.Urug.Cardiol.]]></abbrev-journal-title>
<issn>1688-0420</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Uruguaya de Cardiología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1688-04202018000200075</article-id>
<article-id pub-id-type="doi">10.29277/cardio.33.2.5</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Sustitución valvular aórtica quirúrgica en pacientes de mediana edad. Prótesis mecánica versus biológica]]></article-title>
<article-title xml:lang="en"><![CDATA[Surgical aortic valve replacement in middle-aged patients. Mechanical versus biological prosthesis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramos]]></surname>
<given-names><![CDATA[María Victoria]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Casa de Galicia Centro Cardiovascular ]]></institution>
<addr-line><![CDATA[Montevideo ]]></addr-line>
<country>Uruguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2018</year>
</pub-date>
<volume>33</volume>
<numero>2</numero>
<fpage>75</fpage>
<lpage>98</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S1688-04202018000200075&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S1688-04202018000200075&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S1688-04202018000200075&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: Los pacientes de mediana edad que requieren sustitución valvular aórtica quirúrgica constituyen un grupo en el que la decisión del tipo de prótesis a implantar (biológica o mecánica) continúa siendo discutida. Se realizó una búsqueda bibliográfica con el objetivo de determinar cuál de las prótesis beneficia más a este grupo. Cuando se evalúan las bioprótesis, la principal dificultad radica en el deterioro estructural, más intenso cuanto más joven es el paciente y que puede requerir reintervención por disfunción severa. Por otro lado, las prótesis mecánicas implican anticoagulación de por vida, con los riesgos derivados de este tratamiento. En el presente artículo se analiza la evidencia más significativa para orientar al médico clínico en la toma de decisiones.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Summary: Middle-aged patients who require surgical aortic valve replacement constitute a group in wich the decision of the type of prosthesis to implant (biological or mechanical) continues to be discussed. A bibliographic search was carried out in order to determine which of the prostheses benefits this group. When evaluating bioprostheses, the main difficulty lies in structural deterioration, more intense in the younger patient and that may require reintervention due to severe dysfunction. On the other hand, the mechanical prosthesis involve anticoagulation for life, with the risks derived from this treatment. The present article analyzes the most significant evidence to guide the clinical doctor in decision making process.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Válvula aórtica-prótesis valvulares cardíacas]]></kwd>
<kwd lng="es"><![CDATA[Bioprótesis-efectos adversos]]></kwd>
<kwd lng="es"><![CDATA[Pacientes-mediana edad]]></kwd>
<kwd lng="en"><![CDATA[Aortic valve-heart valve prosthesis]]></kwd>
<kwd lng="en"><![CDATA[Bioprosthesis-adverse effects]]></kwd>
<kwd lng="en"><![CDATA[Patients-middle aged]]></kwd>
</kwd-group>
</article-meta>
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