<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2393-6797</journal-id>
<journal-title><![CDATA[Revista Uruguaya de Medicina Interna ]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Urug. Med. Int.]]></abbrev-journal-title>
<issn>2393-6797</issn>
<publisher>
<publisher-name><![CDATA[Sociedad de Medicina Interna del Uruguay]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2393-67972021000200061</article-id>
<article-id pub-id-type="doi">10.26445/06.02.9</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Trombofilias, esterilidad, infertilidad y tratamiento de reproducción asistida]]></article-title>
<article-title xml:lang="en"><![CDATA[Thrombophilias, sterility, infertility and assisted reproductive treatment]]></article-title>
<article-title xml:lang="pt"><![CDATA[Trombofilias, esterilidade, infertilidade e tratamento reprodutivo assistido]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chaquiriand]]></surname>
<given-names><![CDATA[Virginia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de la República Facultad de Medicina Hospital de Clínicas]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Uruguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>07</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>07</month>
<year>2021</year>
</pub-date>
<volume>6</volume>
<numero>2</numero>
<fpage>61</fpage>
<lpage>66</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S2393-67972021000200061&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S2393-67972021000200061&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S2393-67972021000200061&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: La esterilidad se define como la no obtención del embarazo luego de un año de relaciones sexuales sin protección en parejas heterosexuales. Puede afectar hasta un 15 a 20% de las parejas en edad reproductiva en algún momento de la vida. Las causas de esterilidad se dividen en: factor masculino, factor femenino, causa mixta y esterilidad sin causa aparente. Se ha planteado que las trombofilias hereditarias y adquiridas, podrían estar involucradas en su etiología; y que las distintas estrategias de tratamiento de éstas (ácido acetil salicílico, heparina de bajo peso molecular, corticoides, hidroxicloroquina, entre otros) podrían mejorar los resultados de las técnicas de reproducción asistida.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Sterility is defined as failure to achieve pregnancy after one year of unprotected sexual intercourse in heterosexual couples. It can affect up to 15-20% of couples of reproductive age at some point in life. The causes of sterility are divided into: male factor, female factor, mixed cause and sterility with no apparent cause. It has been suggested that hereditary and acquired thrombophilias could be involved in its etiology; and that the different treatment strategies for these (acetylsalicylic acid, low molecular weight heparin, corticosteroids, hydroxychloroquine, among others) could improve the results of assisted reproductive techniques.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo:  Esterilidade é definida como o fracasso em engravidar após um ano de relação sexual desprotegida em casais heterossexuais. Pode afetar até 15-20% dos casais em idade reprodutiva em algum momento da vida. As causas da esterilidade são divididas em: fator masculino, fator feminino, causa mista e esterilidade sem causa aparente. Foi sugerido que trombofilias hereditárias e adquiridas podem estar envolvidas em sua etiologia; e que as diferentes estratégias de tratamento para estes (ácido acetilsalicílico, heparina de baixo peso molecular, corticosteroides, hidroxicloroquina, entre outros) poderiam melhorar os resultados das técnicas de reprodução assistida.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[esterilidad]]></kwd>
<kwd lng="es"><![CDATA[infertilidad]]></kwd>
<kwd lng="es"><![CDATA[trombofilia]]></kwd>
<kwd lng="en"><![CDATA[sterility]]></kwd>
<kwd lng="en"><![CDATA[infertility]]></kwd>
<kwd lng="en"><![CDATA[thrombophilia]]></kwd>
<kwd lng="pt"><![CDATA[esterilidade]]></kwd>
<kwd lng="pt"><![CDATA[infertilidade]]></kwd>
<kwd lng="pt"><![CDATA[trombofilia]]></kwd>
</kwd-group>
</article-meta>
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<source><![CDATA[Acta Obstet Gynecol Scand]]></source>
<year>2018</year>
<volume>97</volume>
<numero>9</numero>
<issue>9</issue>
<page-range>1061-72</page-range></nlm-citation>
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