<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2393-6797</journal-id>
<journal-title><![CDATA[Revista Uruguaya de Medicina Interna ]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Urug. Med. Int.]]></abbrev-journal-title>
<issn>2393-6797</issn>
<publisher>
<publisher-name><![CDATA[Sociedad de Medicina Interna del Uruguay]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2393-67972021000200031</article-id>
<article-id pub-id-type="doi">10.26445/06.02.4</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Pre-eclampsia y Trombofilia hereditaria]]></article-title>
<article-title xml:lang="en"><![CDATA[Pre-eclampsia and hereditary thrombophilia]]></article-title>
<article-title xml:lang="pt"><![CDATA[Pré-eclâmpsia e trombofilia hereditária]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Santos]]></surname>
<given-names><![CDATA[Carolina De los]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Larraburu]]></surname>
<given-names><![CDATA[Soledad]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González]]></surname>
<given-names><![CDATA[Valentín]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de la República Facultad de Medicina Hospital de Clínicas]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Uruguay</country>
</aff>
<aff id="Af1">
<institution><![CDATA[,maristevenazzi@gmail.com  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>07</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>07</month>
<year>2021</year>
</pub-date>
<volume>6</volume>
<numero>2</numero>
<fpage>31</fpage>
<lpage>35</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S2393-67972021000200031&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S2393-67972021000200031&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S2393-67972021000200031&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: Los trastornos hipertensivos del embarazo constituyen una de las principales causas de mortalidad materna y perinatal en todo el mundo. Se ha estimado que la pre-eclampsia complica del 2 al 8% de los embarazos a nivel mundial. Se han asociado múltiples factores de riesgo: antecedentes de pre-eclampsia, hipertensión arterial crónica, diabetes pre-gestacional, gestación múltiple, enfermedad renal crónica y algunas enfermedades autoinmunes (como el síndrome antifosfolípidico y el lupus eritematoso sistémico). Se realiza una revisión sobre las medidas generales de prevención de la pre-eclampsia.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Hypertensive disorders of pregnancy are one of the leading causes of maternal and perinatal mortality worldwide. Pre-eclampsia has been estimated to complicate 2-8% of pregnancies worldwide. Multiple risk factors have been associated: history of pre-eclampsia, chronic arterial hypertension, pre-gestational diabetes, multiple gestation, chronic kidney disease, and some autoimmune diseases (such as antiphospholipid syndrome and systemic lupus erythematosus). A review is carried out on the general measures of prevention of pre-eclampsia.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo: Os distúrbios hipertensivos da gravidez são uma das principais causas de mortalidade materna e perinatal em todo o mundo. Estima-se que a pré-eclâmpsia complique de 2 a 8% das gestações em todo o mundo. Múltiplos fatores de risco têm sido associados: história de pré-eclâmpsia, hipertensão arterial crônica, diabetes pré-gestacional, gestação múltipla, doença renal crônica e algumas doenças autoimunes (como síndrome antifosfolípide e lúpus eritematoso sistêmico). É realizada uma revisão das medidas gerais de prevenção da pré-eclâmpsia.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[pre-eclampsia]]></kwd>
<kwd lng="es"><![CDATA[trombofilia hereditaria]]></kwd>
<kwd lng="en"><![CDATA[pre-eclampsia]]></kwd>
<kwd lng="en"><![CDATA[hereditary thrombophilia]]></kwd>
<kwd lng="pt"><![CDATA[pré-eclâmpsia]]></kwd>
<kwd lng="pt"><![CDATA[trombofilia hereditária]]></kwd>
</kwd-group>
</article-meta>
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