<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2393-6797</journal-id>
<journal-title><![CDATA[Revista Uruguaya de Medicina Interna ]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Urug. Med. Int.]]></abbrev-journal-title>
<issn>2393-6797</issn>
<publisher>
<publisher-name><![CDATA[Sociedad de Medicina Interna del Uruguay]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2393-67972019000100005</article-id>
<article-id pub-id-type="doi">10.26445/04.01.1</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Estudio descriptivo de pacientes con EPOC asistidos en medicina interna del Hospital Pasteur de Montevideo: características demográficas y comorbilidades]]></article-title>
<article-title xml:lang="en"><![CDATA[Descriptive study of patients with COPD assisted in internal medicine of the Hospital Pasteur of Montevideo: demographic characteristics and comorbidities]]></article-title>
<article-title xml:lang="pt"><![CDATA[Estudo descritivo de pacientes com DPOC atendidos em medicina interna do Hospital Pasteur de Montevidéu: características demográficas e comorbidades]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Correa]]></surname>
<given-names><![CDATA[Selene]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gonzaléz]]></surname>
<given-names><![CDATA[Mariana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Betolaza]]></surname>
<given-names><![CDATA[Sofía de]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Spiess]]></surname>
<given-names><![CDATA[Cecilia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Perera]]></surname>
<given-names><![CDATA[Patricia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Algorta]]></surname>
<given-names><![CDATA[Santiago]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Goñi]]></surname>
<given-names><![CDATA[Mabel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de la República Facultad de Medicina Policlínica de EPOC. Clínica Médica &#8220;2&#8221;. Hospital Pasteur]]></institution>
<addr-line><![CDATA[Montevideo ]]></addr-line>
<country>Uruguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<volume>4</volume>
<numero>1</numero>
<fpage>5</fpage>
<lpage>15</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S2393-67972019000100005&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S2393-67972019000100005&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S2393-67972019000100005&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción: La EPOC es una enfermedad de alta prevalencia, base inflamatoria y compromiso sistémico, asociada a múltiples comorbilidades que afectan sinérgicamente la calidad de vida y pronóstico de los pacientes.  Objetivo:  Describir las principales características demográficas de una población de pacientes con EPOC. Valorar las comorbilidades más frecuentes y su relación con la enfermedad.  Materiales y métodos:  Estudio observacional, descriptivo y transversal desde el 1° de octubre de 2015 al 31 de diciembre de 2016. Criterios de inclusión: ambos sexos, mayores de 40 años, clínica y factores de riesgo compatibles o diagnóstico previo de EPOC. Criterios de exclusión: deterioro cognitivo moderado-severo, pacientes postrados, embarazadas, tuberculosis pulmonar activa, enfermedades neuromusculares. Muestreo realizado por conveniencia.  Resultados: 61 pacientes captados, se confirmó EPOC por espirometría en 42. Edad media 63 años (± 11) y predominó en el sexo masculino (24, 57.1 %). La mayoría tenía bajo nivel de instrucción (primaria incompleta en 15 pacientes, 35.7%). El tabaquismo se constató en el 100% como factor de riesgo, alcoholismo en 14 pacientes (33.3%) y obesidad en 10 (23.8%), con un IMC máximo de 41 y una media de 25.79 ± 6.83 Kg/m2. De las comorbilidades indagadas, la HTA es la más frecuente, le siguen las enfermedades respiratorias asociadas (asma, intersticiopatías y SAHOS) en 6 pacientes, 14,3%. Otras comorbilidades como dislipemia (8 pacientes, 19%), diabetes mellitus (6 pacientes, 14.3%), cardiopatía isquémica (4 pacientes, 9.5%), CBP (3 pacientes, 7.1%), infección por VIH (2 pacientes, 4.8%) y enfermedad renal crónica (1 paciente, 2.4%) fueron también analizadas.  Conclusiones:  La edad media y el sexo coinciden con los datos internacionales. Predominó el nivel de instrucción bajo y medio, lo que tiene implicancias en la comprensión de la enfermedad y las comorbilidades. El principal factor de riesgo para el desarrollo de la enfermedad es el tabaquismo. El 100% de los pacientes tenían comorbilidades. La HTA y el alcoholismo son las más frecuentes. Existe una relación significativa entre EPOC y la presencia de alteraciones endocrino-metabólicas como obesidad, dislipemia y diabetes. La presencia de otras enfermedades respiratorias constituyen un desafío diagnóstico. La relación con CBP es siempre estrecha por compartir el tabaquismo como agente etiológico. El número y tipo de comorbilidades se relaciona con el pronóstico vital a corto plazo cuando los pacientes son hospitalizados, en una exacerbación de la EPOC.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  COPD is a disease of high prevalence, inflammatory base and systemic involvement, associated with multiple comorbidities that synergistically affect the quality of life and prognosis of patients.  Objective:  To describe the main demographic characteristics of a population of patients with COPD. Assess the most frequent comorbidities and their relationship with the disease.  Materials and methods:  Observational, descriptive and cross-sectional study from October 1, 2015 to December 31, 2016. Inclusion criteria: both sexes, over 40 years of age, clinical and compatible risk factors or previous diagnosis of COPD. Exclusion criteria: moderate-severe cognitive impairment, prostrate patients, pregnant women, active pulmonary tuberculosis, neuromuscular diseases. Sampling done for convenience.  Results:  61 patients received, COPD was confirmed by spirometry in 42. Mean age was 63 years (± 11) and it predominated in males (24, 57.1%). The majority had low educational level (incomplete primary in 15 patients, 35.7%). Smoking was found in 100% as a risk factor, alcoholism in 14 patients (33.3%) and obesity in 10 (23.8%), with a maximum BMI of 41 and a mean of 25.79 ± 6.83 Kg / m2. Of the comorbidities investigated, hypertension is the most frequent, followed by associated respiratory diseases (asthma, interstitial diseases and OSAHS) in 6 patients, 14.3%. Other comorbidities such as dyslipidemia (8 patients, 19%), diabetes mellitus (6 patients, 14.3%), ischemic heart disease (4 patients, 9.5%), PBC (3 patients, 7.1%), HIV infection (2 patients, 4.8%) and chronic kidney disease (1 patient, 2.4%) were also analyzed.  Conclusions:  Average age and sex coincide with international data. Low and medium level of education predominated, which has implications in the understanding of the disease and comorbidities. The main risk factor for the development of the disease is smoking. 100% of patients had comorbidities. HTA and alcoholism are the most frequent. There is a significant relationship between COPD and the presence of endocrine-metabolic disorders such as obesity, dyslipidemia and diabetes. The presence of other respiratory diseases is a diagnostic challenge. The relationship with CBP is always close because of sharing smoking as an etiological agent. The number and type of comorbidities are related to short-term vital prognosis when patients are hospitalized, in an exacerbation of COPD.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo:  Introdução:  A DPOC é uma doença de alta prevalência, base inflamatória e envolvimento sistêmico, associada a múltiplas comorbidades que afetam sinergicamente a qualidade de vida e o prognóstico dos pacientes.  Objetivo: Descrever as principais características demográficas de uma população de pacientes com DPOC. Avaliar as comorbidades mais frequentes e sua relação com a doença.  Materiais e métodos:  Estudo observacional, descritivo e transversal, de 1º de outubro de 2015 a 31 de dezembro de 2016. Critérios de inclusão: ambos os sexos, maiores de 40 anos, fatores de risco clínicos e compatíveis ou diagnóstico prévio de DPOC. Critérios de exclusão: comprometimento cognitivo moderado-grave, pacientes prostrados, gestantes, tuberculose pulmonar ativa, doenças neuromusculares. Amostragem feita por conveniência.  Resultados: dos 61 pacientes atendidos, a DPOC foi confirmada pela espirometria em 42. A idade média foi de 63 anos (± 11) e predominou no sexo masculino (24, 57,1%). A maioria tinha baixo nível educacional (primário incompleto em 15 pacientes, 35,7%). O tabagismo foi encontrado em 100% como fator de risco, alcoolismo em 14 pacientes (33,3%) e obesidade em 10 (23,8%), com IMC máximo de 41 e média de 25,79 ± 6,83 Kg / m2. Das comorbidades investigadas, a hipertensão arterial é a mais frequente, seguida das doenças respiratórias associadas (asma, doenças intersticiais e SAHOS) em 6 pacientes, 14,3%. Co-morbidades e dislipidemia (8 pacientes, 19%), diabetes mellitus (6 pacientes, 14,3%), doença isquémica cardíaca (4 pacientes, 9,5%), PFC (3 pacientes, 7,1%), infecção por VIH (2 pacientes, 4,8%) e doença renal crônica (1 paciente, 2,4%) também foram analisados.  Conclusões: Idade média e sexo coincidem com dados internacionais. Baixa e média escolaridade predominou, o que tem implicações na compreensão da doença e comorbidades. O principal fator de risco para o desenvolvimento da doença é o tabagismo. 100% dos pacientes tinham comorbidades. A HTA e o alcoolismo são os mais frequentes. Existe uma relação significativa entre a DPOC e a presença de distúrbios endócrino-metabólicos, como obesidade, dislipidemia e diabetes. A presença de outras doenças respiratórias é um desafio diagnóstico. A relação com o CBP está sempre próxima, por compartilhar o tabagismo como agente etiológico. O número e o tipo de comorbidades estão relacionados ao prognóstico vital de curto prazo quando os pacientes são hospitalizados, em uma exacerbação da DPOC.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[EPOC]]></kwd>
<kwd lng="es"><![CDATA[comorbilidades]]></kwd>
<kwd lng="en"><![CDATA[COPD]]></kwd>
<kwd lng="en"><![CDATA[comorbidities]]></kwd>
<kwd lng="pt"><![CDATA[DPOC]]></kwd>
<kwd lng="pt"><![CDATA[comorbidades]]></kwd>
</kwd-group>
</article-meta>
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