<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2301-1254</journal-id>
<journal-title><![CDATA[Anales de la Facultad de Medicina]]></journal-title>
<abbrev-journal-title><![CDATA[Anfamed]]></abbrev-journal-title>
<issn>2301-1254</issn>
<publisher>
<publisher-name><![CDATA[Universidad de la República. Facultad de Medicina]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2301-12542025000101205</article-id>
<article-id pub-id-type="doi">10.25184/anfamed2025v12n1a8</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[¿Quiénes prescriben cannabis medicinal en Uruguay?: estudio preliminar sobre actitudes y conocimientos de los prescriptores]]></article-title>
<article-title xml:lang="en"><![CDATA[Who prescribe medical cannabis in Uruguay?: attitudes and knowledge of prescribers: a preliminar study]]></article-title>
<article-title xml:lang="pt"><![CDATA[Quem prescreve cannabis medicinal no Uruguai?: atitudes e conhecimento dos prescritores: estudo preliminar]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[De Santis]]></surname>
<given-names><![CDATA[Agustina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Wood]]></surname>
<given-names><![CDATA[Irene]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Galarraga]]></surname>
<given-names><![CDATA[Florencia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Jara]]></surname>
<given-names><![CDATA[Javier]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mansilla]]></surname>
<given-names><![CDATA[Santiago]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Tamosiunas]]></surname>
<given-names><![CDATA[Gustavo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Speranza]]></surname>
<given-names><![CDATA[Noelia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de la República Facultad de Medicina Unidad Académica de Farmacología y Terapéutica]]></institution>
<addr-line><![CDATA[Montevideo ]]></addr-line>
<country>Uruguay</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de la República Facultad de Medicina Unidad Académica de Métodos Cuantitativos]]></institution>
<addr-line><![CDATA[Montevideo ]]></addr-line>
<country>Uruguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<volume>12</volume>
<numero>1</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S2301-12542025000101205&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S2301-12542025000101205&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S2301-12542025000101205&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción:  El interés terapéutico por los cannabinoides de uso medicinal se ha incrementado recientemente.  Objetivo:  Realizar un estudio preliminar para conocer la prevalencia y el perfil de los prescriptores de cannabis medicinal en Uruguay durante mayo-julio 2022 y la respuesta clínica observada.  Materiales y métodos:  Se realizó un estudio observacional, descriptivo y transversal, a través de una encuesta.  Resultados:  Se analizaron 88 respuestas, siendo 21 médicos prescriptores (prescriptores) y 67 no prescriptores (no prescriptores) de cannabinoides de uso medicinal. El principal motivo de no prescripción es la falta de conocimiento científico. Los prescriptores se concentran en Montevideo, presentan mayor edad, antigüedad profesional, grado de especialización, y conocimiento de la normativa que los no prescriptores. Se prescriben mayormente productos nacionales registrados con cannabidiol respondiendo a la demanda de los pacientes. Los usos terapéuticos principales de cannabinoides de uso medicinal son el tratamiento del dolor, epilepsia, enfermedades neurodegenerativas y espasticidad, en su mayoría indicaciones fuera de prospecto. Los encuestados refieren en sus pacientes mejoría con cannabinoides de uso medicinal y efectos adversos leves.  Conclusiones:  Los resultados preliminares obtenidos sugieren que la prescripción de cannabinoides de uso medicinal en Uruguay predomina en ciertas especialidades médicas, que coinciden con sus indicaciones aprobadas. En su mayoría, la indicación surge por iniciativa de los pacientes, y la más frecuente fue el tratamiento del dolor, seguido de enfermedades neurodegenerativas, oncológicas. La percepción de mejoría y las expectativas sobre el tratamiento fueron altas entre los prescriptores en la muestra estudiada. Es necesario realizar este estudio a mayor escala, continuar investigando en efectividad y seguridad de cannabinoides de uso medicinal, e incorporar a la formación médica su perfil farmacológico y usos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction:  The interest in the therapeutic effects of medicinal cannabis has increased.  Objective:  Conduct a preliminary study to know the prevalence and profile of medicinal cannabis prescribers in Uruguay during may-july 2022, as well as to know the clinical response obtained.  Material and methods:  An observational, descriptive and cross-sectional study was carried out, through a survey.  Results:  Eighty eight responses to the survey were analyzed, being twenty-one medicinal cannabis prescribers (prescribers), and 67 non-medicinal cannabis prescribers (non-prescribers). The main reason for not medicinal cannabis prescription is the lack of scientific knowledge. The prescribers are concentrated in Montevideo, are older, with higher professional seniority, degree of specialization and regulatory knowledge than non-prescribers. Registered national products with cannabidiol are the most prescribed, in response to patients&#8217; demands. The most reported therapeutic uses of medicinal cannabis is the treatment of pain, epilepsy, neurodegenerative diseases, and spasticity, most of them off label uses. The prescribers reported improvement in their patients and mild adverse reactions.  Conclusions:  The preliminar results obtained suggest that prescription of medicinal cannabis in Uruguay predominates in certain medical specialties, which coincide with their approved indications. For the most part, the indication arises at the initiative of the patients, and the most frequent was the treatment of pain, followed by neurodegenerative and oncological diseases. The perception of improvement and expectations about the treatment were high among prescribers in the studied sample. It is necessary to conduct this study on a larger scale, continue researching the effectiveness and safety of medicinal cannabis, and incorporate its pharmacological profile and uses into medical training.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo  Introdução:  O interesse pelos efeitos terapêuticos do cannabis medicinal tem aumentado.  Objetivo:  O objetivo deste estudo é fazer uma pesquisa preliminar para conhecer a prevalência e o perfil dos prescritores de cannabis medicinal no Uruguai durante maio-julho 2022, bem como conhecer a resposta clínica obtida.  Material e métodos:  Foi realizado um estudo observacional, descritivo e transversal, por meio de inquérito.  Resultados:  Foram analisadas 88 respostas à pesquisa, sendo 21 prescritores de cannabis medicinal (prescritores) e 67 não prescritores de cannabis medicinal (não prescritores). O principal motivo para a não prescrição de cannabis medicinal é a falta de conhecimento científico. Os prescritores estão concentrados em Montevidéu, são mais velhos, com maior antiguidade profissional, grau de especialização e conhecimento regulatório do que os não prescritores. Os produtos nacionais registrados com canabidiol são os mais prescritos, atendendo às demandas dos pacientes. Os usos terapêuticos mais relatados da cannabis medicinal são o tratamento da dor, epilepsia, doenças neurodegenerativas e espasticidade, a maioria deles usos off label. Os prescritores relataram melhora em seus pacientes e reações adversas leves.  Conclusões:  Os resultados obtidos neste estudo preliminar sugerem que a prescrição de cannabis medicinal no Uruguai predomina em determinadas especialidades médicas, o que coincide com as indicações aprovadas. Na maioria das vezes, a indicação surge por iniciativa dos pacientes, sendo o mais frequente o tratamento da dor, seguido das doenças neurodegenerativas e oncológicas. A percepção de melhora e as expectativas em relação ao tratamento foram elevadas entre os prescritores na amostra estudada. É necessário fazer este estudo numa maior escala, continuar a investigar a eficácia e segurança da canábis medicinal e incorporar o seu perfil farmacológico e utilizações na formação médica.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Cannabis medicinal]]></kwd>
<kwd lng="es"><![CDATA[Cannabidiol]]></kwd>
<kwd lng="es"><![CDATA[Prescripción médica]]></kwd>
<kwd lng="es"><![CDATA[Dolor]]></kwd>
<kwd lng="es"><![CDATA[Epilepsia]]></kwd>
<kwd lng="es"><![CDATA[Uso fuera de prospecto]]></kwd>
<kwd lng="en"><![CDATA[Medical marijuana]]></kwd>
<kwd lng="en"><![CDATA[Cannabidiol]]></kwd>
<kwd lng="en"><![CDATA[Prescription]]></kwd>
<kwd lng="en"><![CDATA[Pain]]></kwd>
<kwd lng="en"><![CDATA[Epilepsy]]></kwd>
<kwd lng="en"><![CDATA[Off label use]]></kwd>
<kwd lng="pt"><![CDATA[Maconha medicinal]]></kwd>
<kwd lng="pt"><![CDATA[Canabidiol]]></kwd>
<kwd lng="pt"><![CDATA[Prescrição]]></kwd>
<kwd lng="pt"><![CDATA[Dor]]></kwd>
<kwd lng="pt"><![CDATA[Epilepsia]]></kwd>
<kwd lng="pt"><![CDATA[Uso off label]]></kwd>
</kwd-group>
</article-meta>
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</ref-list>
</back>
</article>
