<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1688-9339</journal-id>
<journal-title><![CDATA[Odontoestomatología]]></journal-title>
<abbrev-journal-title><![CDATA[Odontoestomatología]]></abbrev-journal-title>
<issn>1688-9339</issn>
<publisher>
<publisher-name><![CDATA[Facultad de Odontología - Universidad de la República]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1688-93392020000300094</article-id>
<article-id pub-id-type="doi">10.22592/ode2020n36a11</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Protocolo de follow-up en leucoplasia proliferativa multifocal para evitar progresión maligna. Presentación de un caso clínico]]></article-title>
<article-title xml:lang="pt"><![CDATA[Protocolo de acompanhamento em leucoplasia proliferativa multifocal para evitar progressão malignos. Apresentação de um caso clínico]]></article-title>
<article-title xml:lang="en"><![CDATA[Follow up protocol in proliferative multifocal leukoplakia to avoid malignant transformation. A case report]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Figueroa]]></surname>
<given-names><![CDATA[Luciana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Tortone]]></surname>
<given-names><![CDATA[Marco]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gilligan]]></surname>
<given-names><![CDATA[Gerardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pánico]]></surname>
<given-names><![CDATA[Rene]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Nacional de Córdoba Facultad de Odontología ]]></institution>
<addr-line><![CDATA[Córdoba ]]></addr-line>
<country>Argentina</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Nacional de Córdoba Facultad de Odontología ]]></institution>
<addr-line><![CDATA[Córdoba ]]></addr-line>
<country>Argentina</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Nacional de Córdoba Facultad de Odontología Cátedra de Estomatología]]></institution>
<addr-line><![CDATA[Córdoba ]]></addr-line>
<country>Argentina</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad Nacional de Córdoba Facultad de Odontología Cátedra de Estomatología]]></institution>
<addr-line><![CDATA[Córdoba ]]></addr-line>
<country>Argentina</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<volume>22</volume>
<numero>36</numero>
<fpage>94</fpage>
<lpage>102</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S1688-93392020000300094&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S1688-93392020000300094&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S1688-93392020000300094&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: La leucoplasia proliferativa multifocal (LPM) es considerada uno de los desórdenes potencialmente malignos (DPM) con mayor tasa de transformación carcinomatosa. La terapéutica es sumamente dificultosa ya que en la mayoría de los casos las lesiones son refractarias. El objetivo de este trabajo es presentar un caso de LPM y su evolución, destacando la importancia del seguimiento clínico mediante protocolos de follow up. Se presentó a la consulta una paciente de 75 años con múltiples lesiones queratóticas y verrugosas en toda la mucosa bucal y con un patrón de crecimiento proliferativo. Las biopsias y el contexto clínico permitieron encuadrarlo dentro del diagnóstico de LPM. La paciente adhirió a un protocolo estricto y hasta el momento se presenta libre de lesiones carcinomatosas. Este trabajo resalta el cuidadoso acompañamiento de los pacientes con este diagnóstico a fin de detectar precozmente carcinomas incipientes pudiendo mejorar el pronóstico de esta entidad.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo: A leucoplasia proliferativa multifocal (LPM) é considerada um dos distúrbios orais potencialmente malignos (DOPM) com a maior taxa de transformação maligna. A terapêutica é extremamente difícil, pois na maioria dos casos as lesões são refratárias. O objetivo deste estudo é relatar um caso de LPM e sua evolução, destacando a importância do monitoramento clínico por meio de protocolos exaustivos de acompanhamento. Uma mulher de 75 anos com múltiplas lesões queratóticas e verrugas por toda a mucosa oral e com um padrão de crescimento proliferativo foi apresentada à consulta. As biópsias e o contexto clínico permitiram ajustá-lo ao diagnóstico de LPM. O paciente aderiu a um protocolo rigoroso e, até o momento, está livre de lesões carcinomatosas. Este trabalho destaca o acompanhamento cuidadoso dos pacientes com esse diagnóstico, a fim alcançar a detecção precoce do carcinoma epidermoide oral e, consequentemente, melhorar o prognóstico.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Proliferative multifocal leukoplakia (PML) is considered one of the oral potentially malignant disorders (OPMD) with the highest malignant transformation rate. Therapeutics is extremely difficult since, in most cases, the lesions are refractory. This study aims to report a case of PML and its evolution, highlighting the importance of clinical monitoring through comprehensive follow-up protocols. A 75-year-old female with multiple keratotic and verrucous lesions with a proliferative growth pattern throughout the oral mucosa. The biopsies and the clinical context allowed clinicians to diagnose it as PML. The patient adhered to a strict protocol and so far has no carcinomatous lesions. This report highlights the careful monitoring of patients with PML to achieve early detection of oral squamous cell carcinoma and, consequently, improve prognosis.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[leucoplasia]]></kwd>
<kwd lng="es"><![CDATA[carcinoma de células escamosas]]></kwd>
<kwd lng="es"><![CDATA[seguimiento]]></kwd>
<kwd lng="es"><![CDATA[leucoplasia proliferativa]]></kwd>
<kwd lng="pt"><![CDATA[leucoplasia]]></kwd>
<kwd lng="pt"><![CDATA[carcinoma de células escamosas]]></kwd>
<kwd lng="pt"><![CDATA[seguimento]]></kwd>
<kwd lng="pt"><![CDATA[leucoplasia proliferativa]]></kwd>
<kwd lng="en"><![CDATA[leukoplakia]]></kwd>
<kwd lng="en"><![CDATA[oral squamous cell carcinoma]]></kwd>
<kwd lng="en"><![CDATA[follow-up]]></kwd>
<kwd lng="en"><![CDATA[proliferative leukoplakia]]></kwd>
</kwd-group>
</article-meta>
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<article-title xml:lang=""><![CDATA[Proliferative verrucous leukoplakia high incidence of gingival squamous cell carcinoma]]></article-title>
<source><![CDATA[J Oral Pathol Med]]></source>
<year>2003</year>
<volume>32</volume>
<numero>7</numero>
<issue>7</issue>
<page-range>379-82</page-range></nlm-citation>
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</back>
</article>
