<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1688-0420</journal-id>
<journal-title><![CDATA[Revista Uruguaya de Cardiología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev.Urug.Cardiol.]]></abbrev-journal-title>
<issn>1688-0420</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Uruguaya de Cardiología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1688-04202017000200150</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Análisis prospectivo sobre incidencia acumulada de delirio en el posoperatorio de cirugía cardíaca]]></article-title>
<article-title xml:lang="en"><![CDATA[Prospective analysis of cumulative incidence of delirium in the postoperative period of cardiac surgery]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Dotti]]></surname>
<given-names><![CDATA[Silvana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Montes De Oca]]></surname>
<given-names><![CDATA[Omar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bigalli]]></surname>
<given-names><![CDATA[Daniel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez]]></surname>
<given-names><![CDATA[Favio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Russo]]></surname>
<given-names><![CDATA[Nicolás]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pouso]]></surname>
<given-names><![CDATA[Marcos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Centro Cardiovascular Casa de Galicia Centro de Investigación Cardiovascular del Uruguay ]]></institution>
<addr-line><![CDATA[Montevideo ]]></addr-line>
<country>Uruguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2017</year>
</pub-date>
<volume>32</volume>
<numero>2</numero>
<fpage>150</fpage>
<lpage>157</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S1688-04202017000200150&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S1688-04202017000200150&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S1688-04202017000200150&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Fundamento:  el delirio es un síndrome de diagnóstico clínico que afecta a un importante porcentaje de pacientes que cursan posoperatorio de cirugía cardíaca, pudiendo desencadenar consecuencias negativas. A pesar de su elevada incidencia se encuentra subdiagnosticado. En Uruguay no existen datos de injuria encefálica aguda a modo de delirio en el posoperatorio de cirugía cardíaca.  Métodos:  se realizó un estudio prospectivo, descriptivo, con elementos analíticos en una cohorte de 93 pacientes consecutivos a quienes se les realizó cirugía cardíaca durante el período comprendido entre el 25 de julio de 2016 y el 27 de setiembre de 2016. Se realizó el análisis en dos etapas del posoperatorio. Etapa 1: despertar anestésico, con delirio versus sin delirio; y etapa 2: durante la internación desde el período posextubación hasta el alta sanatorial, con delirio versus sin delirio. Para la evaluación se utilizó la escala de sedación Ramsay y la escala CAM (Confussion Assesment Method). El trabajo estadístico se realizó mediante análisis univariado, prueba U Mann Whitney y prueba de t.  Resultados:  la incidencia de delirio al despertar fue de 51,6% y estuvo relacionada con estadía más prolongada en unidad de cuidados intensivos (UCI) (82,3 ± 72,1 vs 54,5 ± 19,9 horas (p=0,02)). La incidencia de delirio luego de la extubación hasta el alta sanatorial fue de 41,9%, siendo este grupo de pacientes más añosos, con edad de 69,3 ± 10,1 vs 60,9 ± 10 años (p ?0,001); tuvieron mayor tiempo de asistencia respiratoria mecánica 11,47 ± 12,68 vs 7,49 ± 6,11 horas (p=0,019), y una mayor estadía en UCI: 87,9 ± 78,3 vs 55,1 ± 20,7 horas (p=0,003). No se encontraron diferencias significativas en las demás variables analizadas.  Conclusiones:  la incidencia acumulada de delirio fue de 51,6% al despertar y de 41,9% durante la internación desde el período posextubación. La presencia de delirio al despertar se asoció con mayor estadía en UCI. Luego de la extubación, la presencia de delirio se asoció a mayor edad, mayor tiempo de asistencia respiratoria mecánica y estadía más prolongada en UCI.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Summary  Background:  delirium is a clinical diagnosis syndrome that affects a significant percentage of patients who undergo postoperative cardiac surgery, which may lead to negative consequences. Despite its high incidence, it is underdiagnosed. In Uruguay, there is no data on acute encephalic injury as a delirium in the postoperative period of cardiac surgery.  Methods:  a prospective, descriptive study with analytical elements was carried out. A cohort of 93 consecutive patients who underwent cardiac surgery during the period from July 25, 2016 to September 27, 2016 was included. The analysis was made in two stages. The first stage was during the anesthetic awakening, with two possible outcomes: with delirium vs. without delirium. The second stage was during the hospitalization from the post-extubation period to hospital discharge: with delirium vs. without delirium. For the evaluation, the Ramsay sedation scale and the Confussion Assesment Method (CAM) scale were used. Statistical analysis was performed using a univariate analysis, Mann Whitney U Test and t Test.  Results:  the incidence of delirium on awakening was 51.6% and was related to longer intensive care unit (ICU) stay (82.3 ± 72.1 vs 54.5 ± 19.9 hours (p = 0.02)). The incidence of delirium during hospitalization from the post-extubation period to hospital discharge was 41.9%. This group of patients was more aged on average (with ages of 69.3 ± 10.1 vs 60.9 ± 10 years (p ? 0.001)), had a longer time in mechanical ventilation (11.47 ± 12.68 vs 7.49 ± 6.11 hours (p = 0.019)) and a longer ICU stay: (87.9 ± 78.3 vs 55.1 ± 20.7 hours (p = 0.003)). No significant differences were found in the other variables analyzed.  Conclusions  The cumulative incidence of delirium was 51.6% on awaking and 41.9% during hospitalization from the post-extubation period to hospital discharge. The presence of delirium on awakening was associated with longer ICU stay. In the second stage, the presence of delirium was associated with older age, longer time of mechanical ventilation and longer stay in ICU.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[delirio]]></kwd>
<kwd lng="es"><![CDATA[sedación]]></kwd>
<kwd lng="es"><![CDATA[cirugía cardíaca]]></kwd>
<kwd lng="es"><![CDATA[período posoperatorio]]></kwd>
<kwd lng="es"><![CDATA[incidencia]]></kwd>
<kwd lng="en"><![CDATA[delirium]]></kwd>
<kwd lng="en"><![CDATA[sedation]]></kwd>
<kwd lng="en"><![CDATA[cardiac surgery]]></kwd>
<kwd lng="en"><![CDATA[postoperative period]]></kwd>
<kwd lng="en"><![CDATA[incidence]]></kwd>
</kwd-group>
</article-meta>
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