<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1688-0390</journal-id>
<journal-title><![CDATA[Revista Médica del Uruguay]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Méd. Urug.]]></abbrev-journal-title>
<issn>1688-0390</issn>
<publisher>
<publisher-name><![CDATA[Sindicato Médico del Uruguay]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1688-03902021000101502</article-id>
<article-id pub-id-type="doi">10.29193/rmu.37.1.11</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[¿Por qué continuamos transfundiendo dos unidades de sangre a la vez si con una sola podría ser suficiente?]]></article-title>
<article-title xml:lang="en"><![CDATA[Why do we keep transfusing two units of blood at the same time if just one could be enough?]]></article-title>
<article-title xml:lang="pt"><![CDATA[Por que continuamos a transfundir duas unidades de sangue ao mesmo tempo se apenas uma pode ser o suficiente?]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Berro]]></surname>
<given-names><![CDATA[Maximiliano]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez]]></surname>
<given-names><![CDATA[Ismael]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de la República Facultad de Medicina Cátedra de Hemoterapia y Medicina Transfusional, Hospital de Clínicas]]></institution>
<addr-line><![CDATA[Montevideo ]]></addr-line>
<country>Uruguay</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de la República Facultad de Medicina Cátedra de Hemoterapia y Medicina Transfusional. Hospital de Clínicas]]></institution>
<addr-line><![CDATA[Montevideo ]]></addr-line>
<country>Uruguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2021</year>
</pub-date>
<volume>37</volume>
<numero>1</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S1688-03902021000101502&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S1688-03902021000101502&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S1688-03902021000101502&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: La transfusión de sangre ha sido identificada como uno de los procedimientos médicos más sobreutilizados en pacientes hospitalizados. Una estrategia que permitiría reducir la exposición de los pacientes a la sangre es a través de la implementación de una política de transfusión de una sola unidad, en lugar de dos, para pacientes estables, sin hemorragia y con anemia sintomática. La decisión de transfundir sangre es compleja y depende de varios factores, además, los riesgos de la transfusión se deben sopesar contra los beneficios esperados. La transfusión de dos unidades de sangre a la vez ya no se considera una forma de tratamiento &#8220;estándar&#8221; para pacientes anémicos sin sangrado activo. Existe una gran oportunidad para reducir el uso excesivo de la transfusión y fomentar las transfusiones de una sola unidad.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Summary: Blood transfusion has been identified as one of the most overused medical procedures in hospitalized patients. One strategy that would reduce the exposure of patients to blood is through the implementation of a single-unit regime for stable patients without bleeding and with symptomatic anemia. The decision to transfuse blood is complex and depends on several factors, in addition, the risks of transfusion must be weighed against the expected benefits. Transfusion of two units of blood at the same time is no longer considered a &#8220;standard&#8221; form of treatment for anemic patients without active bleeding. There is a great opportunity to reduce the overuse of transfusion and encourage single-unit transfusions.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo: A transfusão de sangue foi identificada como um dos procedimentos médicos usados de mais em pacientes hospitalizados. Uma estratégia que reduziria a exposição dos pacientes ao sangue é por meio da implantação de uma política transfusional de unidade única para pacientes estáveis, sem sangramento e com anemia sintomática. A decisão de transfundir sangue é complexa e depende de vários fatores, além disso, os riscos da transfusão devem ser analisados em relação aos benefícios esperados. A transfusão de duas unidades de sangue ao mesmo tempo não é mais considerada uma forma &#8220;padrão&#8221; de tratamento para pacientes anêmicos sem sangramento ativo. Há uma grande oportunidade de reduzir o uso excessivo de transfusões e incentivar as transfusões de uma única unidade.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Transfusión sanguínea]]></kwd>
<kwd lng="es"><![CDATA[Estándares de referencia]]></kwd>
<kwd lng="en"><![CDATA[Blood transfusion]]></kwd>
<kwd lng="en"><![CDATA[Reference standards]]></kwd>
<kwd lng="pt"><![CDATA[Transfusão de sangue]]></kwd>
<kwd lng="pt"><![CDATA[Padrões de referencia]]></kwd>
</kwd-group>
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