<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2393-6797</journal-id>
<journal-title><![CDATA[Revista Uruguaya de Medicina Interna ]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Urug. Med. Int.]]></abbrev-journal-title>
<issn>2393-6797</issn>
<publisher>
<publisher-name><![CDATA[Sociedad de Medicina Interna del Uruguay]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2393-67972019000300035</article-id>
<article-id pub-id-type="doi">10.26445/04.03.4</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Migración infrecuente de tuberculosis extrapulmonar primaria: reporte de caso]]></article-title>
<article-title xml:lang="en"><![CDATA[Infrequent migration of primary extrapulmonary tuberculosis: case report]]></article-title>
<article-title xml:lang="pt"><![CDATA[Migração infreqüente de tuberculose extrapulmonar primária: relato de caso]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Salas Pérez]]></surname>
<given-names><![CDATA[Marcia Darmelly]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rivera Torrejón]]></surname>
<given-names><![CDATA[Oscar Orlando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chambergo Michilot]]></surname>
<given-names><![CDATA[Diego]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Paucar Pongo]]></surname>
<given-names><![CDATA[Ubaldo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Nacional Dos de Mayo  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Perú</country>
</aff>
<pub-date pub-type="pub">
<day>01</day>
<month>12</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>01</day>
<month>12</month>
<year>2019</year>
</pub-date>
<volume>4</volume>
<numero>3</numero>
<fpage>35</fpage>
<lpage>42</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S2393-67972019000300035&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S2393-67972019000300035&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S2393-67972019000300035&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  A nivel global, la tuberculosis de localización extrapulmonar representa el 18% de los casos de la enfermedad, teniendo como lugares más frecuentes de afectación la pleura (54%), ganglios (11,1%), sistema nervioso central (9%) y sistema osteoarticular (3,6%), entre otros. La manifestación clínica de la meningoencefalitis tuberculosa se presenta con fiebre, cefalea, vómitos, alteración de la conciencia, fotofobia, afectación de pares craneales, alteraciones audiovisuales, signos de irritación meníngea y focalización neurológica. La tuberculosis ostearticular es consecuencia de una diseminación hemática, linfática o, excepcionalmente, por inoculación directa. La clínica es insidiosa, con dolor, inflamación y disminución del rango articular, pudiendo presentar abscesos y cavidades supurativas. Sin embargo, existen otros síntomas de baja frecuencia de aparición, dificultando el diagnóstico adecuado. Se describe el caso clínico infrecuente de tuberculosis extrapulmonar, destacando la diseminación de Mycobacterium tuberculosis con foco en la articulación coxofemoral izquierda hacia meninges y cerebro, y el uso inapropiado del tratamiento con corticoesteroides en un paciente seronegativo para VIH.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Extrapulmonary tuberculosis accounts for 18% of tuberculosis cases, with the pleura (54%), lymph nodes (11.1%), central nervous system (9%) and osteoarticular system (3.6%) as sites of involvement, among others. Clinical manifestations of tuberculous meningoencephalitis are fever, headache, vomiting, altered consciousness, photophobia, cranial nerve involvement, audiovisual alterations, signs of meningeal irritation and neurological focalization. Ostearticular tuberculosis is the result of hematic, lymphatic dissemination or, exceptionally, by direct inoculation. The clinic is insidious, with pain, inflammation and diminished joint range, and can present abscesses and suppurative cavities. However, there are other symptoms of low frequency of appearance, making the diagnosis difficult. For this reason, an infrequent clinical case of extrapulmonary tuberculosis is described, highlighting the spread of Mycobacterium tuberculosis with focus on the left coxofemoral joint to the meninges and brain, and the inappropriate use of adrenal cortex hormones therapy in a seronegative patient for HIV.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo: A tuberculose extrapulmonar é responsável por 18% dos casos de tuberculose, com pleura (54%), linfonodos (11,1%), sistema nervoso central (9%) e sistema osteoarticular (3,6%) como locais de envolvimento. entre outros. A manifestação clínica da meningoencefalite tuberculosa é febre, dor de cabeça, vômitos, consciência alterada, fotofobia, comprometimento dos nervos cranianos, alteraçõesaudiovisuais, sinais de irritação meníngea e focalização neurológica. A tuberculose ostearticular é o resultado de disseminação hemática, hemática ou, excepcionalmente, por inoculaçãodireta. A clínica é insidiosa, comdor, inflamação e diminuição do leque de articulações, podendoapresentarabscessos e cavidades supurativas. No entanto, existemoutrossintomas de baixafrequência de aparecimento, dificultando o diagnóstico. Por esta razão, nósdescrevemosum caso clínico raro de tuberculoseextrapulmonar, com destaque para a disseminação de Mycobacterium tuberculosis com foco naarticulação do quadrilesquerdo para meninges e cérebro, e uso inadequado de corticoterapiaem paciente soronegativa HIV.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[tuberculosis]]></kwd>
<kwd lng="es"><![CDATA[meningoencefalitis]]></kwd>
<kwd lng="es"><![CDATA[tuberculosis osteoarticular]]></kwd>
<kwd lng="es"><![CDATA[glucocorticoides]]></kwd>
<kwd lng="es"><![CDATA[dexametasona]]></kwd>
<kwd lng="en"><![CDATA[tuberculosis]]></kwd>
<kwd lng="en"><![CDATA[meningoencephalitis]]></kwd>
<kwd lng="en"><![CDATA[osteoarticular]]></kwd>
<kwd lng="en"><![CDATA[glucocorticoids]]></kwd>
<kwd lng="en"><![CDATA[dexamethasone]]></kwd>
<kwd lng="pt"><![CDATA[tuberculose]]></kwd>
<kwd lng="pt"><![CDATA[meningoencefalite]]></kwd>
<kwd lng="pt"><![CDATA[tuberculoseosteoarticular]]></kwd>
<kwd lng="pt"><![CDATA[glicocorticóides]]></kwd>
<kwd lng="pt"><![CDATA[dexametasona]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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