<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2301-1254</journal-id>
<journal-title><![CDATA[Anales de la Facultad de Medicina]]></journal-title>
<abbrev-journal-title><![CDATA[Anfamed]]></abbrev-journal-title>
<issn>2301-1254</issn>
<publisher>
<publisher-name><![CDATA[Universidad de la República. Facultad de Medicina]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2301-12542025000201401</article-id>
<article-id pub-id-type="doi">10.25184/anfamed2025v12n2a1</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Secuelas osteoarticulares por sepsis meningococica. Tratamiento con Ilizarov: reporte de caso y revisión literatura]]></article-title>
<article-title xml:lang="en"><![CDATA[Osteoarticular sequelae due to meningococcal septicemia treatment with Ilizarov: case report and literature review]]></article-title>
<article-title xml:lang="pt"><![CDATA[Complicações osteoarticulares devido à sepse meningocócica tratamento de Ilizarov. Relato de caso e revisão da literatura]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fernandez]]></surname>
<given-names><![CDATA[Renzo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Filippini]]></surname>
<given-names><![CDATA[Juan Pedro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Russi]]></surname>
<given-names><![CDATA[Martin]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Perez]]></surname>
<given-names><![CDATA[Maria Elena]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de la República Facultad de Medicina Clinica de Traumatología y Ortopedia]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Uruguay</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de la República Facultad de Medicina ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Uruguay</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de la República Facultad de Medicina ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Uruguay</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de la República Facultad de Medicina ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Uruguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<volume>12</volume>
<numero>2</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_arttext&amp;pid=S2301-12542025000201401&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_abstract&amp;pid=S2301-12542025000201401&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.edu.uy/scielo.php?script=sci_pdf&amp;pid=S2301-12542025000201401&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción:  La Sepsis Meningococica cuando se complica con una Coagulación Intravascular Diseminada es una entidad clínica de gran mortalidad, especialmente en niños menores de 1-2 años, hasta hace algunas décadas en que los tratamientos médicos consiguieron mejorar mucho su pronóstico vital. Esto ha hecho que actualmente veamos más secuelas osteoarticulares a medio-largo plazo.  Objetivo: Reportar el caso de una paciente que sufrió Sepsis Meningococica con prolongado seguimiento tratada de forma aguda y en la evolución mediante reconstrucción ósea con Ilizarov y realizar una revisión bibliográfica no sistematizada de las secuelas osteoarticulares de la SM.  Resultados:  La corrección de las deformidades del miembro inferior izquierdo en todos los planos fue aceptable, se logro un miembro axado y funcional con un rango de movilidad de rodilla de 90 grados de flexión y 170 grados de extension , la cual le permite a la paciente la marcha asistida con una prótesis adaptada al muñón del miembro inferior derecho.  Conclusiones: La valoración debe de ser multidisciplinaria desde el inicio de la enfermedad. En la etapa temprana se deben solucionar las complicaciones inmediatas relacionadas a la coagulación intravascular diseminada y en el seguimiento a largo plazo las vinculadas a las secuelas osteoarticulares. El método de Ilizarov surge como una alternativa versátil, ya que permite manejar todos los planos de deformidad y a la vez realizar alargamientos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction:  Meningococal sepsis when complicated by disseminated intravascular coagulation is a clinical entity with high mortality, especially in children under 1-2 years of age, until a few decades ago when medical treatments managed to greatly improve their vital prognosis. This has meant that we currently see more osteoarticular sequelae in the medium-long term.  Objective:  To report the case of a patient who suffered meningococal sepsis with prolonged follow up treated acutely and in the evolution by bone reconstruction with Ilizarov and to carry out a non-systematized bibliographic review of the osteoarticular sequelae of meningococal sepsis.  Results:  The correction of the left lower limb deformities in all planes was acceptable, an axed and functional MII was achieved with a range of knee mobility of 90 degrees of flexion and 170 degrees of extension, allows the patient to walk assisted with a prosthesis adapted to the right stump.  Conclusions:  The assessment must be multidisciplinary from the beginning of the disease. At the early stage, immediate complications related to disseminated intravascular coagulation must be resolver and in long-term follow up those linked to osteoarticular sequelae must be resolved. The Ilizarov method emerges as a versatile alternative, since it allows all planes of deformity to be managed and at the same time to perform lengthening.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo  Introdução:  A sepse meningocócica, quando complicada por coagulação intravascular disseminada, é uma condição clínica de alta mortalidade, especialmente em crianças com menos de 1 a 2 anos de idade, até algumas décadas atrás, quando os tratamentos médicos conseguiram melhorar significativamente seu prognóstico vital. Isso fez com que atualmente observemos mais sequelas osteoarticulares a médio e longo prazo.  Objetivo:  Relatar o caso de uma paciente que sofreu sepse meningocócica com acompanhamento prolongado, tratada de forma aguda e, na evolução, por meio de reconstrução óssea com Ilizarov, além de realizar uma revisão bibliográfica não sistematizada sobre as sequelas osteoarticulares da sepse meningocócica.  Resultados:  A correção das deformidades do membro inferior esquerdo em todos os planos foi satisfatória, obtendo-se um membro alinhado e funcional, com um arco de movimento do joelho de 90 graus de flexão e 170 graus de extensão, o que permite à paciente a marcha assistida com uma prótese adaptada ao coto do membro inferior direito.  Conclusões:  A avaliação deve ser multidisciplinar desde o início da doença. Na fase inicial, devem ser tratadas as complicações imediatas relacionadas à coagulação intravascular disseminada, e, no seguimento a longo prazo, aquelas vinculadas às sequelas osteoarticulares. O método de Ilizarov surge como uma alternativa versátil, pois permite corrigir deformidades em todos os planos e, ao mesmo tempo, realizar alongamentos ósseos.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Reconstrucción]]></kwd>
<kwd lng="es"><![CDATA[Ilizarov]]></kwd>
<kwd lng="es"><![CDATA[Deformidades Angulares]]></kwd>
<kwd lng="es"><![CDATA[Sepsis Meningococica]]></kwd>
<kwd lng="es"><![CDATA[Coagulación Intravascular Diseminada]]></kwd>
<kwd lng="en"><![CDATA[Reconstruction]]></kwd>
<kwd lng="en"><![CDATA[Ilizarov]]></kwd>
<kwd lng="en"><![CDATA[Angular Deformities]]></kwd>
<kwd lng="en"><![CDATA[Meningococcal Sepsis]]></kwd>
<kwd lng="en"><![CDATA[Disseminated Intravascular Coagulation]]></kwd>
<kwd lng="pt"><![CDATA[Reconstrução]]></kwd>
<kwd lng="pt"><![CDATA[Ilizarov]]></kwd>
<kwd lng="pt"><![CDATA[Deformidades Angulares]]></kwd>
<kwd lng="pt"><![CDATA[Sepse Meningocócica]]></kwd>
<kwd lng="pt"><![CDATA[Coagulação Intravascular Disseminada]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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