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Revista Uruguaya de Medicina Interna

On-line version ISSN 2393-6797

Abstract

SMILIANSKY, Natasha et al. Cardiovascular risk, dyslipidemia and indication for statins in a morbidly obese population. Rev. Urug. Med. Int. [online]. 2024, vol.9, e305.  Epub Dec 01, 2024. ISSN 2393-6797.  https://doi.org/10.26445/09.01.8.

Introduction:

Obesity is related to a high cardiovascular risk (CVR). This forces us to take therapeutic and preventive behaviors. The objective of this work is to evaluate cardiovascular risk in a morbidly obese population and assess the correct indication of statins.

Methodology:

Cross-sectional, descriptive, observational study, with the morbidly obese population of the Obesity and Bariatric Surgery Program (POCB) of the Maciel Hospital, from November 2014 to March 2020. CVR was assessed with the calculator of the Pan-American health organization. The indication for statins was considered according to CVR or diagnosis of dyslipidemia.

Results:

478 patients were analyzed, 84.3% were women, the median age was 44 years, and the BMI was 50 kg/m2. A low CVR was calculated for 57% of patients; and high or very high for 37%. The prevalence of dyslipidemia was 84.3%, with a predominance of hypercholesterolemia (33.7%) and atherogenic dyslipidemia (19.5%). 60.6% (290) of patients have an indication for treatment with statins, only 38.9%. (113) receives them. 38.1% (43) achieved therapeutic objectives.

Conclusions:

Obesity presents multiple comorbidities that increase CVR, yet it is underestimated by risk calculators. Pharmacological undertreatment of these patients is evident, not achieving the proposed therapeutic objectives.

Keywords : Obesity; bariatric surgery; dyslipidemia; cardiovascular risk.

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