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Revista Uruguaya de Medicina Interna

On-line version ISSN 2393-6797


LASTRA JAUREGUI, Abel  and  SUAREZ LACABE, Amanda. Recurrent Guillain-Barré syndrome associated with anti-COVID-19 vaccine. Case report. Rev. Urug. Med. Int. [online]. 2023, vol.8, n.3, pp.70-76.  Epub Dec 01, 2023. ISSN 2393-6797.

Guillain-Barré Syndrome is the most frequent cause of acute flaccid paralysis in the world. Its diagnosis is clinical and must be supported by studies of the cerebrospinal fluid and nerve conduction. It is produced as a consequence of a crossed immune response to antigens from different pathogens, and it has also been associated with previous immunizations. There is little literature on its recurrence associated with anti-COVID-19 vaccination in the world, and as far as the authors are aware, this is the only report associated with the Abdala vaccine (CIGB-66). We present the case of a 55-year-old male patient who reported acute loss of muscle strength, who presented complications during his stay in the Intensive Care Unit, associated with mechanical ventilation. The fact that it is so difficult to give a quick and accurate diagnosis, especially in underdeveloped countries, where specialized studies are not always available and an eminently clinical diagnosis must be made motivated the authors to present this atypical case.

Keywords : Guillain-Barré syndrome; recurrence; vaccination; Abdala.

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