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Revista Uruguaya de Medicina Interna

On-line version ISSN 2393-6797


GRANA, Diego et al. COVID-19 and Systemic Autoimmune Diseases, what is the relationship and its consequences?. Rev. Urug. Med. Int. [online]. 2023, vol.8, n.3, pp.26-34.  Epub Dec 01, 2023. ISSN 2393-6797.


Patients with autoimmune system diseases constitute a vulnerable population for the development of SARS-CoV-2 infection.


To determine the incidence of SARS-CoV-2 infection in patients seen at the polyclinic.


Cross-sectional study patients assisted in an autoinmune disease center in the period April 2020-July 2021.


59 patients were analyzed, 19 had flares of the disease in the last year. 12 had SARS CoV-2 infection, 1 was admitted to moderate care. The median age of infected patients was 35 years. 55 received full vaccination.


No association was found between COVID-19 infection and diseases flares as well as an increased rate of hospitalization or death. Lupus patients were the most vulnerable. The controls rate (face-to-face/telephone) was high for the entire population as well as the vaccination rate.

Keywords : COVID; SARS-CoV-2; Autoinmune disease; Inmunosuppressive therapy; Flares; Vaccines..

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