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Revista Uruguaya de Medicina Interna

Print version ISSN 2393-6797On-line version ISSN 2393-6797


ROLDAN, Alicia; FAGUNDEZ, Yohana; SARACHAGA, María Eugenia  and  BRADVICA, Virginia. Muscle amyloidosis. About a clinical case. Rev. Urug. Med. Int. [online]. 2021, vol.6, n.2, pp.96-103.  Epub July 01, 2021. ISSN 2393-6797.

Amyloidosis encompasses various diseases characterized by the extracellular deposition of an abnormal and insoluble (amyloid) protein among the different tissues, causing its progressive dysfunction. The clinical presentation is usually heterogeneous, which determines the delays in diagnosis.

To achieve this, a biopsy of the affected tissue, the demonstration of amyloid deposit and the typing of the protein that constitutes it are required. Early detection allows optimizing the treatment, conditioning the prognosis. Amyloid myopathy associated with plasma cell dyscrasia is an infrequent cause of muscle hypertrophy, for which reason the following article seeks to present a clinical case of it with a subsequent review of the literature.

Keywords : amyloidosis; amyloid myopathy; muscle hypertrophy.

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