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Revista Uruguaya de Medicina Interna

Print version ISSN 2393-6797On-line version ISSN 2393-6797


VUAN, María Fiorella et al. Acquired hemophilia. Presentation of clinical case and review of the bibliography. Rev. Urug. Med. Int. [online]. 2020, vol.5, n.1, pp.41-46.  Epub Mar 01, 2020. ISSN 2393-6797.

Acquired hemophilia is a rare coagulation disorder caused by circulating autoantibodies that inhibit coagulation factors, primarily F VIII. A considerable percentage of patients with acquired hemophilia die due to a late diagnosis with the consequent delay in the start of treatment.

The main goals of treatment are to control bleeding, eradicate the inhibitor and treat underlying disorders that can be identified. We present the case of a 72-year-old woman with a history of rheumatoid arthritis who presented with a coagulopathic hemorrhagic syndrome of spontaneous onset.

Keywords : autoantibodies; factor VIII; Acquired hemophilia.

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