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Revista Uruguaya de Medicina Interna

Print version ISSN 2393-6797On-line version ISSN 2393-6797


SANJINES, Lucía; MARTINEZ, Miguel  and  MAGLIANO, Julio. Dermatitis herpetiformis as a presentation of celiac disease. Rev. Urug. Med. Int. [online]. 2016, vol.1, n.1, pp.3-3. ISSN 2393-6797.

ABSTRACT: Dermatitis herpetiformis (DH) is an autoimmune blistering disease (EAI) that corresponds to the cutaneous manifestation of Celiac Disease (CD), more exactly of gluten intolerance. It is clinically manifested as an itchy papulovesicular rash, primarily located on extensor surfaces of the extremities. The diagnosis is made by histopathological examination of lesional skin and direct immunofluorescence (DIF) of surrounding skin, which shows characteristic findings. In its pathogenesis, genetic, immunologic and factors environmental factors take part. The treatment of choice is gluten-free diet (DEG) and dapsone. It has been reported an association of about 15% between the skin and intestinal involvement, there is so far no prospective study that shows the actual frequency of CD in patients with DH.

Keywords : Dermatitis herpetiformis; Celiac disease; Gluten sensitive enteropathy.

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