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Anales de la Facultad de Medicina

On-line version ISSN 2301-1254


CAMEJO, Natalia et al. Characteristics and management of early breast cancer in elderly women assisted in the Mastology Care Teaching Unit of the Hospital de Clínicas in the period 2011-2018. Anfamed [online]. 2021, vol.8, n.2, e201.  Epub Dec 01, 2021. ISSN 2301-1254.


There are few guidelines for the treatment of breast cancer (BC) in older patients, which can lead to under- or over-treatment.


To understand the characteristics, management and evolution of early BC in older women.

Material and methods:

Observational, descriptive, cross-sectional study. Data were collected on the clinical-pathological characteristics and evolution of patients aged 70 years or older, treated for BC in the period from 1/1/ 2011 to 31/12/ 2018, at the Hospital de Clínicas. Descriptive statistical tools were used and the Kaplan-Meier method was applied to calculate the overall survival (OS) rate.


31 patients were included; median age at diagnosis was 76.8 years old; the clinical-pathological characteristics were: ductal carcinoma: 71%; HG 1-2: 74.2%; stage I: 54.8%; no axillary metastases: 80.6%; HER2-ER/PR+ 80.6%; HER2+ 16.7%, and triple negative 3.2%. Of all the patients, 29% were diagnosed through screening and 74.2% were treated according to current guidelines, while 38.7% were under-treated and 16.1% over-treated. The median OS was 98.7 months.


A minority of patients were diagnosed by screening, the most frequent histological type was ductal and the prevalence of HER2-RE/RP+ tumors was higher than in younger patients. Most patients received standard treatment.

Keywords : breast carcinoma; elderly; massive screening; diagnosis; combined therapy and psychological distress.

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