Abstract

MANTA, Bruno; SARKISIAN, Armen G.; GARCIA-FONTANA, Barbara  and  PEREIRA-PRADO, Vanesa. Pathophysiology of COVID-19. Odontoestomatología [online]. 2022, vol.24, n.39, e312.  Epub June 01, 2022. ISSN 0797-0374.  https://doi.org/10.22592/ode2022n39e312.

Coronavirus disease is a respiratory infection caused by the SARS-CoV-2 virus, which causes a cascade of systemic events, affecting various organs and tissues. Understanding the pathophysiology of COVID-19 is essential to treat patients and understand the causes of the complications in a significant number of recovered patients. This article presents a review of the effects of infection on various organs and systems that will be useful as reference material for healthcare professionals and medical students. To this end, a literature search was conducted in PubMED, Scielo, Google Scholar, Cochrane, and Springer Link portals, as well as in the pre-publication scientific repositories bioRxiv (“bioarchives”) and medRxiv (“med-archives”) databases. From about 200,000 papers, 100 articles were selected for this review based on their relevance or suggestions from experts in the field.

Keywords : SARS-CoV-2; patophysiology; COVID-19; ACE2.

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