Abstract

GONZALEZ UMPIERREZ, Natalia  and  BEOVIDE CORTEGOSO, Verónica. Profile of oral squamous cell carcinoma at the Anatomic Pathology Laboratory of the School of Dentistry of Universidad de la República, 1982-2015 period. Odontoestomatología [online]. 2020, vol.22, n.36, pp.34-43.  Epub Dec 01, 2020. ISSN 0797-0374.  https://doi.org/10.22592/ode2020n36a5.

Oral squamous cell carcinoma is the most frequent malignant oral pathology, mainly associated with tobacco, alcohol, and human papillomavirus.

This study aimed to determine the profile of this pathology at the Laboratory of Anatomic Pathology of the School of Dentistry of Universidad de la República between 1982 and 2015. A retrospective, cross-sectional, analytical study was conducted. Statistical analysis performed using the Cox model, Fisher’s exact test, and the Kaplan-Meier method. Of 207 cases, 59.9% were men and 98.5% older than 40. It is usually located on the tongue, with a predominance of histopathologically well and moderately differentiated carcinomas. There was an association between histopathological grade, gender, and age, with an average survival time of 2.36 years and a 43% five-year survival rate. The study allowed us to determine the situation of this pathology in a reference health service and create a database for subsequent studies.

Keywords : head and neck squamous cell carcinoma; epidemiology; survival.

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