Abstract

GARCIA, Pedro Emilio; AVILA, Rodolfo Esteban  and  SAMAR, María Elena. Case report of Basal cell adenocarcinoma of the parotid gland: clinicopathological and immunohistochemical study. Odontoestomatología [online]. 2018, vol.20, n.31, pp.71-77. ISSN 0797-0374.  https://doi.org/10.22592/ode2018n31a8.

Basal cell adenocarcinoma is an epithelial neoplasm with the cytological characteristics of a basal cell adenoma but with a morphological pattern of infiltrative growth indicative of malignancy. It is often difficult to diagnose it because of its low incidence. The objective of this study is to identify the morphological and immunohistochemical characteristics that aid its diagnosis. A parotid tumor was resected in a 52-year-old patient; postoperative biopsy and immunostaining with Ki-67, CK19, p63 and α-smooth muscle actin were performed. The diagnosis was basal cell adenocarcinoma invading the tumor capsule, periglandular fat and lymph nodes. Immunolabeling with Ki-67, CK19, p63 and α-smooth muscle actin was positive. Subsequently, maxillary sinus metastasis was diagnosed. Given the morphological characteristics, elevated Ki-67 expression and metastasis, this is a malignant tumor, which differentiates it from the basal cell adenoma.

Keywords : parotid; basal cell adenocarcinoma; diagnosis.

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