Abstract

ALGORTA, Agustina et al. Leukocyte and platelet rich fibrin for the treatment of oronasal fistula in canines. Veterinaria (Montev.) [online]. 2025, vol.61, n.223, e502.  Epub June 01, 2025. ISSN 0376-4362.  https://doi.org/10.29155/vet.61.223.8.

Platelet-rich fibrin (L-PRF) is a second-generation blood derivative that can be utilized as a biological filler due to the dense fibrin network formed, acting as a scaffold for cells and sustained release of growth factors, aiding in wound healing. In this study, two clinical cases presented at the Odontostomatology Service of Facultad de Veterinaria, Udelar, involving patients with oro-nasal fistula (ONF) were evaluated. The affected tooth was extracted, and ONF closure was achieved using a mucoperiosteal flap and placement of L-PRF in the tooth socket to promote healing. Favorable outcomes were observed during postoperative follow-ups at days 7, 14, and 30, with complete closure and no complications or recurrences in both clinical cases. In these cases, the use of L-PRF placed with the mucoperiosteal flap was able to withstand oral mechanical forces, with no suture dehiscence or ONF recurrence, resulting in satisfactory healing. The use of this regenerative technique appears to offer a new approach for alveolar defect closure, with advantages including its speed, cost-effectiveness, simplicity, ease of implementation in a veterinary clinic, safety, and low risk.

Keywords : Periodontal disease; Veterinary dentistry; Blood products.

        · abstract in Spanish | Portuguese     · text in Spanish     · Spanish ( pdf )