Abstract

CARZOLI, A; KUHLSEN, M  and  PESSINA, P. Usefulness of cappilary zone electrophoresis in the diagnosis of non-effusive Feline Infectious Peritonitis (PIF): a case study. Veterinaria (Montev.) [online]. 2021, vol.57, n.216, e401.  Epub Dec 01, 2021. ISSN 0376-4362.  https://doi.org/10.29155/vet.57.216.5.

Feline infectious peritonitis (PIF) is an infectious disease which has a high mortality rate compared to other infectious diseases among feline population. It clinically manifested under two forms, effusive or non-effusive. PIF’s diagnosis, mainly the non-effusive form, is a clinical challenge based on symptoms, viral detection and laboratory findings. In this regard, the albumin/globulin ratio and the increase on the γ globulin fraction of the capillary zone electrophoresis (PEF) are important and complementary indicators for the antemortem diagnosis of PIF. This job’s objective was to exhibit a feline clinical case clinically diagnosed with non-effusive PIF in which the PEF, along with other complementary routine tests, allowed to reach a definitive diagnosis. PEF’s results showed a polyclonal peak on the γ globulin fraction, a decreased serum albumin concentration and an albumin/globulin ratio of 0,23. Based on these results we discuss how the PEF, mainly on the non-effusive form of PIF, can support this disease diagnosis allowing to dictate an accurate prognosis and helping the clinical veterinarian on therapeutic decisions.

Keywords : Electrophoretic proteinogram; Capillary zone electrophoresis; Feline infectious peritonitis; Diagnosis.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )