SciELO - Scientific Electronic Library Online

vol.57 issue215Susceptibility profile and associated factors analysis of Rhipicephalus microplus for five chemical groups on field populations from the north of Uruguay author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand



Related links


Veterinaria (Montevideo)

Print version ISSN 0376-4362On-line version ISSN 1688-4809


BAZZANO, Valentin et al. Molecular detection of Hepatozoon felis in anemic cats in Uruguay. Veterinaria (Montev.) [online]. 2021, vol.57, n.215, e509.  Epub June 01, 2021. ISSN 0376-4362.

Hepatozoonosis is a parasitic disease caused by Hepatozoon spp. In general, it has a subclinical progression, and its symptoms are associated with an induced immunodeficiency triggered by a concomitant disease. The aim of this study was to detect by PCR the presence of Hepatozoon spp. in domestic cats from Uruguay. A total of 230 blood samples were analyzed obtained in nine of the 19 departments of Uruguay. Only were included samples from cats with early diagnosis of clinical anemia. For molecular diagnosis, two PCRs targeting two overlapping regions of 18S rRNA gene for Hepatozoon spp. were carried out. Nine out of 230 samples were positive for Hepatozoon spp., resulting in an infection frequency of 3.91%. The obtained sequences revealed 99.10 to 100% identity with Hepatozoon felis sequences registered in GenBank. Moreover, the phylogenetic analysis showed that the sequences obtained in this study clustered, with a high Bootstrap support with sequences of H. felis from different continents. To our knowledge, this is the first report of H. felis infecting domestic cats in Uruguay.

Keywords : Hepatozoonosis; Hepatozoon felis; PCR; cats; Uruguay; anemia.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )