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Archivos de Medicina Interna

Print version ISSN 0250-3816On-line version ISSN 1688-423X

Abstract

LOPEZ LOCANTO, Óscar. Pharmacological therapy of Alzheimer’s disease and other dementias. Arch. Med Int [online]. 2015, vol.37, n. 2, pp.61-67. ISSN 0250-3816.

Increased life expectancy brings a result, the increase of chronic diseases in the elderly, prevailing including dementia. Treating them requires a multidimensional approach. This time we will focus on pharmacological treatment of them. Once the diagnosis of dementia, it is appropriate to initiate treatment with acetylcholinesterase inhibitors and/or memantine accordingly. While these drugs do not reverse the cognitive symptoms, slow the progression of the disease. We should note in principle, contraindications, drug interactions and monitor the occurrence of adverse effects. During follow-up the patient must apply functional and cognitive tests to assess the effectiveness of prescription medicines. Currently under study are supposedly curative medicine that targets amyloid and tau protein.

Keywords : Dementia; Alzheimer’s disease; Anticholinesterase drugs; Memantine.

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