Resumo

OLIVER, Carolina et al. Autologous transplant of Haematopoietic Stem Cells in Patients with Aggressive Non Hodgkin Lymphoma: Experience of a center. Arch. Med Int [online]. 2015, vol.37, n. 1, pp.1-6. ISSN 0250-3816.

Introduction: Autologous Hematopoietic Stem Cell Transplantation is part of the treatment of patients with aggressive lymphomas in partial response or relapsed. Objectives: To evaluate the responses and survival in aggressive NHL patients transplanted in Hospital Británico. Material and Methods: Retrospective study of patients with aggressive NHL that were transplanted into... between 01/01/1995 and 07/01/2013. Total 65 patients. Results: 95% achieved a complete remission after Auto-SCT and 5% partial remission. With a median follow up of 74 months (5-219), the median OS has not been reached. The estimated mean is 145 months (122-169) with a 5-year OS of 71% and 60% at 10 years. The median DFS has not been reached, at 5 years is 60 % and at 10 years is 58 %. Conclusions: Autologous Hematopoietic Stem Cell Transplantation is a useful therapeutic tool. The results of our group are comparable to those reported by international groups with low procedure-related mortality.

Palavras-chave : Autologous Stem Cell Trasnplantation; Non Hodgkin Lymphoma.