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Archivos de Medicina Interna

Print version ISSN 0250-3816On-line version ISSN 1688-423X

Abstract

SCHWEDT, Emma et al. First National Consensus on Proteinuria in the Diagnosis and Assessment of Chronic Kidney Disease in Adults. Arch. Med Int [online]. 2012, vol.34, n.1, pp.2-2. ISSN 0250-3816.

ABSTRACT: Arch Med Interna 2012 - 34(1):03-11 Through PubMed review and opinion of experts the authors concluded that proteinuria and albuminuria are diagnostic markers of chronic kidney disease (CKD), are indicators of progression and therefore a therapeutic goal, and are also risk markers of death and CV disease both in the general population and in patients with CKD. These results were confirmed by using the dipstick, proteinuria/creatininuria (P/C) or albuminuria/creatininuria (A/C) ratios in single urine sample with reference to the 24 hours (gold standard) collected urine. The A/C ratio seems to be the ideal method because it will be the easiest to standardize, but their cost is higher, and the P/C ratio is a good predictor at one lower cost. The dipstick test have 29% false positive but if we are strict in collecting the urine sample and the reading is automated it would reduce the possibility of error and the variability of results. Pre-analytical, analytical and post-analytical stages of the proteinuria and albuminuria measurements in laboratory were established by consensus to clarify the diagnosis and evolution of CKD.

Keywords : consenso; proteinuria; tiras reactivas de orina; cociente proteinuria/creatininuria.

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