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Archivos de Medicina Interna

Print version ISSN 0250-3816On-line version ISSN 1688-423X


ANDRADE, Rodrigo et al. Schönlein-Henoch purpura, presentation in the adult. Arch. Med Int [online]. 2011, vol.33, n.3, pp.71-75. ISSN 0250-3816.

Systemic vasculitis are a group of low prevalence disorders that affect vessels of ifferent caliber, having an heterogeneous clinical presentation. Among these, Schönlein-Henoch Purpura (HSP), defined as a systemic vasculitis of small vessel that present in over 90% of cases in children, with an incidence of 13,5 per 100,000 inhabitants, with a generally benign prognosis. The presentation in adulthood is rare, reaching an incidence of 0.03-0.35/100.000 per inhabitants. It typically presents with palpable purpura, arthritis, abdominal pain and renal involvement. According to different series, the presentation in children and adults is similar, having a less favorable prognosis in adults conditioned by kidney disease. Since no controlled clinical trials are available, current evidence is based solely on expert opinion. Therapeutic approach includes nonsteroidal antiinflammatory drugs (NSAID) corticosteroids, immunosuppressive drugs and in some cases plasmapheresis

Keywords : Vasculitis; Henoch-Schönlein Púrpura.

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