Abstract

AYALA, Santiago  and  CASTROMAN, Pablo. Efecto de la lidocaína intravenosa sobre el control del dolor y el consumo de opiáceos en el postoperatorio. Anest Analg Reanim [online]. 2012, vol.25, n.1, pp.1-6. ISSN 1688-1273.

SUMMARY  Objectives: evaluate the effect of intraoperative intravenous lidocaine (IVL) on postoperative pain, morphine consumption and secondary effects. Methods: a prospective, randomized, controlled, and double-blind study in 23 patients scheduled for transabdominal hysterectomy with general anaesthesia was undertaken. In the IVL group 13 patients received a lidocaine i/v bolus of 1,5 mg/kg before skin incision, followed by continuous i/v infusion until skin closure was finished. In the control group 10 patients received matched saline infusion. Results: IVL group experienced less pain, evaluated by visual numeric scale (VNS), than the control group (p<0,05) at the time of been admitted at the postanesthesia care unit (4,6±4,1 versus 7,9±2), at the first 30 minutes (4,5± 2,3 versus 6,5±1,1), and 24 hours after surgery (2,8±1,7 versus 4,8±2,1). The time that took to have conditions to start PCA (VNS£ 4) was less in IVL group (p<0,05), (62,3±25 versus 105±53,7 minutes). Morphine consumption previous to obtain a VNS= 4 was less in IVL group (p<0,05), (5,1±3,6 versus 9,6±2,5 mg). The amount of morphine administered during the first 24 hours was less in the IVL group (p<0,05), 21,8±12,2 versus 30,6±9,3 mg). Sedation, nausea or vomiting was similar in both groups. Conclusions: patients who received IVL experienced better pain relief and reduced postoperative morphine consumption. No other side effects were noted.

Keywords : INTRAVENOUS LIDOCAINE; POSTOPERATIVE PAIN.

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