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Anestesia Analgesia Reanimación

On-line version ISSN 1688-1273


PRESTES, Ivana et al. Efecto de la circulación extracorpórea sobre la perfusión microvascular en pacientes sometidos a cirugía cardíaca: Resultados preliminares. Anest Analg Reanim [online]. 2011, vol.24, n.1, pp.2-2. ISSN 1688-1273.

SUMMARY  Peripheral hypoperfusion is the final common pathway for effects of extracorporeal circulation, indirectly assessed through peripheral oxygen utilization. The Orthogonal Polarization Spectral Imaging allows direct visualization of what happens in microcirculation. The purpose of this study was to evaluate microcirculation changes in nine patients undergoing cardiac surgery with extracorporeal circulation and its correlation with plasma lactate levels. As a secondary objective: to develop a non-invasive method for monitoring microcirculation in surgical patients. Images of microcirculation were obtained before, during and after extracorporeal circulation, measuring size and flow at this level and its correlation with plasma lactate concentration rates. During extracorporeal circulation there was a significant increase in microvascular flow index, for medium and large sized blood vessels (p£0.05). Flow heterogeneity showed a statistically significant increase during extracorporeal circulation for small vessels, and after performed, for larger sized. There was a trend showing that the higher the microvascular flow index, the higher the peak rates and post-extracorporeal circulation plasma lactate concentrations, though with no statistical significance. Preliminary results presented a pattern of microcirculation alterations caused by increased microvascular flow index and flow heterogeneity. Further studies with larger number of patients is required to confirm or not correlation trends with parameters in peripheral oxigen utilization.

Keywords : Orthogonal Spectral Imaging; microcirculation; Orthogonal Polarization Spectral Imagin; extracorporeal circulation; cardiac surgery ; Orthogonal Spectral Imaging.

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