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Archivos de Pediatría del Uruguay
Print version ISSN 0004-0584On-line version ISSN 1688-1249
Abstract
GARCIA, Sofía; FARIAS, Gastón; MACHADO, Karina and GUTIERREZ, Stella. Oncological diseases in children and adolescents hospitalized in moderate pediatric care of a private health provider: clinical and evolutionary characteristics, 2010-2020. Arch. Pediatr. Urug. [online]. 2025, vol.96, n.1, e304. Epub June 01, 2025. ISSN 0004-0584. https://doi.org/10.31134/ap.96.8.
Introduction:
oncological diseases are rare in pediatric patients but they cause significant morbidity and mortality. They manifest with non-specific symptoms, which facilitates diagnostic delay.
Objective:
understand clinical and evolutionary characteristics of children /adolescents hospitalized for oncological pathologies in a private health provider between 2010 and 2020.
Methodology: Retrospective descriptive cohort study, including children under 18 years of age hospitalized for oncological diseases between 01/01/2010 and 12/31/2020. Their medical records were reviewed. The following were described: epidemiological, clinical and evolutionary characteristics.
Results:
during the evaluated time, 61 patients were hospitalized: 39 with solid tumors, 22 hematological. The incidence was 14/100,000, with an average of 5 cases/year. The average age at diagnosis was 5.9 years, 59% were under 5 years old. The most common types of cancer were: leukemia and neuroblastoma. The most frequent manifestations in hematological tumors were: fever and nonspecific symptoms; in solid tumors those linked to location. In 35 children the diagnosis was made in less than 30 days. Forty-seven patients received chemotherapy, of which 34 presented febrile neutropenia. 33 patients were cured, 2 remain in remission, 10 relapsed, and 16 died.
Conclusions:
the incidence of oncological diseases in the period analyzed was similar to that reported in the whole country. The most common type was leukemia. It predominated in children under 5 years of age. More than half were cured, a quarter of the patients died, results similar to those in higher-income countries. These results allow us to improve the care provided to these patients and their families.
Keywords : Medical Oncology; Incidence; Febrile Neutropenia; Child; Adolescent.