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Archivos de Pediatría del Uruguay
Print version ISSN 0004-0584On-line version ISSN 1688-1249
Abstract
ROSA, Daniele Da; LORENZO, Martín; GAGLIARDI, Tatiana and POSE, Guillermo. Neonatal hyperthyroidism: a clinical case study. Arch. Pediatr. Urug. [online]. 2024, vol.95, n.2, e310. Epub Dec 01, 2024. ISSN 0004-0584. https://doi.org/10.31134/ap.95.2.9.
Neonatal hyperthyroidism is generally caused by the transplacental passage of TSH receptor-stimulating antibodies (TSI) in children of mothers with Graves Basedow disease. We present a clinical case of a newborn diagnosed with neonatal hyperthyroidism. This is a term newborn patient that showed symptoms of polypnea, tachycardia and hypertension at 6 days of age; he presented a TSH of 0.01 uIU/ml in the paraclinical cord screening, and a subsequent control in peripheral blood of the same value with T4: 7.75 ng/dl, T3: 12.99 pg/m values. He was treated with methimazole and propranolol with good outcomes. Postnatal control and endocrinological assessment of all newborns born to mothers with hyperthyroidism is important, because these newborns are exposed to significant morbidity and mortality, which suggests the need for early diagnosis and treatment.
Keywords : Hyperthyroidism; Newborns.