Abstract

LOPEZ, Alejandra et al. Multisystem inflammatory syndrome in post-COVID-19 children. 2020-2021. Clinical case report in Montevideo, Uruguay. Arch. Pediatr. Urug. [online]. 2022, vol.93, n.nspe1, e315.  Epub June 01, 2022. ISSN 0004-0584.

The Multisystem Inflammatory Syndrome associated with COVID-19 is a post-infectious presentation, which can be particularly serious, and can produce severe multi-organ dysfunction. We present a report of 6 clinical cases, assisted at the Health Medical Organization (Servicio Médico Integral) in Montevideo, Uruguay, and show the clinical and paraclinical characteristics of this new syndrome, and their clinical evolution. A descriptive observational study is carried out. The mean age was 6 years, mostly females. These patients had a mild to moderate clinical presentation, with good evolution. The main clinical manifestations were: fever, gastrointestinal, mucocutaneous, and ocular compromise; two of these patients had cardiovascular compromise. All had alterations in the paraclinical, increased acute phase reactants were observed.

All patients received intravenous immunoglobulin and corticosteroids, three of them received low molecular weight heparin with a value of D-dimers 5 times higher than the reference value. We do not rule out the impact of early diagnosis and treatment to explain these children´s positive evolution.

Keywords : System inflammatory response syndrome; COVID-19; Kawasaki disease; Child.

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