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Archivos de Pediatría del Uruguay

Print version ISSN 0004-0584On-line version ISSN 1688-1249


DORADO, Natalia; MASTANDREA, Gastón; MAGLIANO, Julio  and  MATELZONAS, Tamy. Neonatal lupus erythematosus: case report. Arch. Pediatr. Urug. [online]. 2016, vol.87, n.1, pp.28-32. ISSN 0004-0584.

Neonatal lupus erythematosus (LEN) is a rare disease that occurs in the newborn given by the transplacental passage of  maternal Anti-Ro/SSA, Anti-La/SSB and Anti-U1-RNP autoantibodies. The main clinical manifestations are dermatologic and cardiac, it may also have hepatic, hematologic or/and neurological ones. The study reports a case of a three month infant who is diagnosed with LEN,   based on the presence of consistent findings of skin lesions and histopathology and immunology compatible findings. In this case, it was not accompanied by systemic manifestations evolution was a favorable one. The case is relevant since it presents an unusual condition that is usually accompanied by characteristic skin lesions, where prognosis is determined by cardiac involvement. In many cases, this enables maternal diagnosis of an asymptomatic autoimmune disease.


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