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Archivos de Pediatría del Uruguay

On-line version ISSN 1688-1249


ZOCALO, Yanina et al. Non-invasive arterial studies for the early detection of vascular changes in children and young people exposed to cardiovascular risk factors and/or systemic diseases. Arch. Pediatr. Urug. [online]. 2015, vol.86, n.3, pp.197-207. ISSN 1688-1249.

Non-invasive, secure, fast and inexpensive systems and studies have been developed in the past decade allowing for early detection of vascular disorders with high sensitivity and specificity. International guidelines aimed at cardiovascular prevention, risk stratification and/or target organ damage assessment in adults recommend non-invasive vascular studies. Recently, vascular evaluation has also been considered in guidelines for cardiovascular prevention in children. Within this context, an arterial evaluation Center (CUiiDARTE-Pediátrico) has been developed and implemented in Pereira-Rossell Hospital to allow children access to non-invasive vascular studies in our country. In the Center, a multi-parameter approach is applied to assess the vascular health condition of children and adolescents by joint analysis of complimentary structural and functional arterial indexes and parameters: (1) detection and evaluation of atherosclerotic plaque composition ("Virtual histology"), (2) arterial wall thickness, (3) global, regional and local arterial stiffness, (4) vascular reactivity (endothelial function), (5) central aortic pressure, (6) pulse wave and waved reflection analysis, (7) ankle-brachial index, (8) arterial blood flow velocities and patterns (arterial Doppler), (9) ambulatory (or hospital) arterial pressure, stiffness and cardiac output monitoring. This study aimed to introduce our vascular approach and non-invasive studies.


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