Abstract

SERRA, Alberto; MACHIN, Cecilia; GUTIERREZ, Carmen  and  MENCHACA, Amanda. Tos convulsa: enfermedad reemergente. Arch. Pediatr. Urug. [online]. 2013, vol.84, n.4, pp.255-262. ISSN 1688-1249.

Summary  Introduction: whopping cough is an acute infection of the airways. Is produced by Bordetella pertussis wich is source of epidemic and sporadic cases. The annual incidence is 60 millons of cases, with 500.000 lethal cases. In last years, cases of whopping cough have raised arround the world, even in countries with high coverage of vaccination. In Uruguay, cases of whopping cough have raised since 2011. Objective: to describe clinical features of children with whopping cough hospitalized in the Intensive Care Unit (ICU) of Centro Hospitalario Pereira Rossell. Methodology: a descriptive study was done between 1st April to 31th December of 2011. Chidren with whopping cough were included. Clinical and laboratory features were registred from clinical records. Results: 34 children were hospitalizaed for whopping cough in ICU. The median age was 2 months (range: 15 days- 60 months). Bordetella pertussis was confirmed in 28 cases and Bordetella parapertussis in 6 cases. In 9 cases a fatal evolution was observed. 10 children developed Pulmonary Hypertension, 7 of these children died. White blood cells (WBC) count at admission was higher in chidren with a letal evolution (72.300 WBC/mm³ versus 34.537 WBC/mm³). Velocity of rising of WBC was higher in those who died (2.305 WBC/hour) than in survivors (495 WBC/hour)(p<0.0001). Conclussion: between 1st April to 31th december of 2011 increased the number of cases of whopping cough wich required admission to the ICU. Count of WBC, velocity of rising of WBC and pulmonary hypertension were identificated as predictors of fatal outcome

Keywords : BORDETELLA PERTUSIS; WHOOPING COUGH; DISEASE OUTBREAKS.

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