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Archivos de Pediatría del Uruguay

On-line version ISSN 1688-1249


GONZALEZ, Virginia; GUTIERREZ, Stella  and  QUIAN, Jorge. Eventos adversos supuestamente atribuibles a la vacunación e inmunización en hijos de madres infectadas con el virus de la inmunodeficiencia humana . Arch. Pediatr. Urug. [online]. 2013, vol.84, n.1, pp.04-09. ISSN 1688-1249.

Summary    Introduction: vaccines are one of the most important and widespread health interventions. Monitoring safety through the registration of adverse events is essential. The children's mother infected with the human immunodeficiency (HIV) virus, exposed, infected or seroreverted are a particular group of individuals within the framework of immunization. The objective of the present study was to describe the frequency of adverse events related to vaccination and immunization (VAERS) in children of mothers infected with HIV. Methodology: a descriptive study was conducted, crosscut between September 1, 2008 and February 28, 2011 at the Pereira Rossell National AIDS Reference Obstetric-Pediatric Center with patients there controlled (infected and non-infected) requiring vaccination in their controls. The percentage and type of events produced were recorded. Results: 189 Patients, 110 (58%) delivered a total of 157 records form. The median age was 2 months (range from 2 months to 17 years), 63% was less than 6 months. Of the 110 children, 34 were infected and non-infected 76. Adverse events were recorded in 49 (44.5%) patients. There were 108 mild events and serious 23. The percentage of VAERS in both groups was similar (p > 0.05). There were no hospitalizations or events difficult to categorize as related to vaccination. Conclusions: vaccines administered in that period were safe with similar VAERS in both groups of patients. Continue to monitor the emergence of VAERS and compare the results every year will be important to update recommendations and ensure the safety of the patients and their caregivers

Keywords : VACCINATION - adverse effects; IMMUNIZATION - adverse effects; HIV INFECTION; CHILDREN.

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