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Archivos de Pediatría del Uruguay

On-line version ISSN 1688-1249

Abstract

GUTIERREZ, Carmen; BELTRAMO, Pilar  and  SCAVONE, Cristina. Hallazgos placentarios en casos de parálisis cerebral. Arch. Pediatr. Urug. [online]. 2009, vol.80, n.3, pp.178-183. ISSN 1688-1249.

Background: there is strong evidence that a great number of cases of cerebral palsy (CP) are originated before birth. There is an interest in determining the causes of this dreadful complication. Many placental lesions have been described in these patients. The purpose of this research is to determine the placental lesions found in our cases of CP and to contribute to the investigation of risk factors. Material and method: the placentas from 39 patients with CP that were born at the Hospital Pereira Rossell in Montevideo were analyzed. The findings were compared to a control group of 75 placentas from patients of a similar gestational age without CP. The authors studied the gestational age, weight at birth, placenta weight and abnormal macroscopic and histological findings. Results: it was relevant from a statistical point of view the findings of: a) large placenta in premature babies; b) prolonged  meconium; c) chorioamnionitis with fetal response in premature babies; d) partial retroplacental hematoma in premature babies with chorioamnionitis; e) fetal thrombotic vasculopathy in full term gestations. Conclusions: placental examination provides valuable evidence in lesions originated before birth in many cases of CP. The results should be included in the clinical history of the pediatric patients. They should be taken into consideration when evaluating patients with CP or with neonatal encephalopathy.

Keywords : CEREBRAL PALSY; BRAIN DAMAGE, CHRONIC; BRAIN DISEASES; PLACENTA-injuries;  INFANT, NEWBORN.

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