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Archivos de Pediatría del Uruguay
On-line version ISSN 1688-1249
Abstract
GARCIA GARIGLIO, Loreley; MACHADO, Maren Karina; BELLO, Osvaldo and SEHABIAGUE, Graciela. Virus respiratorio sincicial en el screening de lactantes febriles entre 29 y 90 días. Arch. Pediatr. Urug. [online]. 2007, vol.78, n.2, pp.133-138. ISSN 1688-1249.
Summary Introduction: fever in infants between 29 and 90 days of age is a challenge to all physicians. It is one of the most common causes of visit at the emergency department. Objective: to compare the incidence between respiratory syncytial viral (RSV) infection in febrile infants between 1 to 3 months and severe bacterial infections (SBI). Material and methods: a descriptive and prospective study was carried out in the Pediatric Emergency Department at the Pereira Rossell Hospital between May 2005 to June 2006. All infants between 1 and 3 months old who had fever without focus were included. A complete history and physical examination including otoscopy were done. The laboratory tests practiced were: complete blood count (CBC), protein C reactive, urianalysis, chest x-rays, cerebrospinal fluid (CSF) analysis, blood, urinary and CSF culture, and nasopharyngeal aspirate for rapid RSV antigen detection via inmunocromatography. All the patients were followed until discharge from the hospital. Results: 186 patients were included, being the medium age of presentation 55 days. Influenza environment was found in 47%; 45% had upper respiratory tract symptoms. RSV infection was detected in 36 patients. 18 urinary tract infections (UTI) and one Meningitis were found. UTI was associated to RSV in one patient. No association was found between RSV with meningitis nor with bacteriemia. This study provides similar results to previous studies showing the low risk of SBI in febrile infants aged 29-90 days with RSV infection. Conclusions: the need for a complete evaluation for SBI in children less then 90 days is still advisable. It is s important to rely on a simple test for RSV diagnosis, especially on winter. However the identification of RSV does not substitute the search for SBI.
Keywords : RESPIRATORY SYNCYTIAL VIRUS, HUMAN; FEVER; INFANT.