Abstract

GUTIERREZ, CARMEN; RODRIGUEZ, ÁNGELES  and  PALENZUELA, SYLVIA. Patología de la aesplenia e hipoesplenia en autopsias pediátricas: Revisión de 12 casos. Arch. Pediatr. Urug. [online]. 2004, vol.75, n.1, pp.51-58. ISSN 1688-1249.

Absence of spleen predisposes individuals to overwhelming sepsis. Any bacterial agent may course rapid onset of septicemia, neumonia, meningitis or septic shock; but the agents most frecquently involved are encapsulated organisms such as neumococcus, haemophilus influenzae type B and meningococcus. Infants and young children are at special risk. Therapies designed to prevent and interrupt overwhelming sepsis have not alltoguether been successful. We revewed 12 autopsy cases of aesplenia-hyposplenia in our files of pediatric pathology, with special consideration of the causes of death and the associated pathology. Six cases of overwhelming sepsis were found

Keywords : SPLEEN-pathology; SPLENOSIS; SEPSIS.

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