Abstract

REAL, Carlos; PARRAGA, Rocío; VAZIRANI, Ravi  and  RESTREPO-CORDOBA, María Alejandra. The electrocardiogram in cardiac amyloidosis: a weapon for the diagnosis suspect of this disease. Rev.Urug.Cardiol. [online]. 2023, vol.38, n.1, e302.  Epub Dec 01, 2023. ISSN 0797-0048.  https://doi.org/10.29277/cardio.38.1.13.

Cardiac amyloidosis (CA) is a serious disease with a poor prognosis if treatment is not started early, so one of the pending issues in this condition is to make an early diagnosis. The electrocardiogram (EKG) is an inexpensive and widely available diagnostic test that can offer differential data when suspecting this disease, being normal in < 5% of these patients. The classic EKG finding is the presence of low voltages in relation to the large hypertrophy seen on imaging tests, as well as the well-known pseudoinfarct pattern. Both findings are more frequent in the light chain subtype of CA, which was the most frequently diagnosed in the past. However, with the growth of noninvasive diagnostic tests, the identification of the transtyretin subtype has grown exponentially, becoming the most frequently diagnosed in our setting. Special attention should be paid to all these electrocardiographic findings, so that this simple diagnostic test can make an important contribution to the early suspicion and diagnosis of CA.

Keywords : Cardiac amyloidosis; Low voltajes; Pseudoinfarct pattern; Electrocardiogram; Atrial fibrillation; Atrioventricular block..

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