Abstract

GONZALEZ, Verónica. Gliflozins: more than oral antidiabetics. A brief review of the literature. Rev.Urug.Cardiol. [online]. 2021, vol.36, n.2, e401.  Epub Aug 01, 2021. ISSN 0797-0048.  https://doi.org/10.29277/cardio.36.2.8.

Diabetes mellitus, heart failure, and chronic kidney disease are highly prevalent in the population. Likewise, these pathologies are included in a “vicious circle” because they share pathophysiological mechanisms that predispose to their coexistence in the same patient, significantly increasing the risk of cardiovascular events. Gliflozins, a group of drugs with benefits in the three mentioned pathologies, have recently been added to the therapeutic arsenal. Knowing how research with these drugs and its mechanisms of action is essential to optimize the treatment of patients.

Keywords : Heart failure; Diabetes mellitus; Cronic kidney disease; Gliflozins.

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