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Revista Uruguaya de Cardiología

Print version ISSN 0797-0048On-line version ISSN 1688-0420


CARAMES, Silvia Noemi; MOLTENI, Susana; MARELICH, Liliana Silvia  and  MARTIRE, Víctor. Pronostic implication of normal gated SPECT studies in patients over 70 years old. Rev.Urug.Cardiol. [online]. 2018, vol.33, n.1, pp.1-19. ISSN 0797-0048.


a normal result in myocardial perfusion scintigraphy (gated-SPECT) has a high negative predictive value for severe coronary artery disease; there is a period of time in which patients remain with a low event rate (less than 1%). However, some evidence suggests that this guarantee period (PG) is not the same in all age groups.


to establish the period of time in which elderly patients (older than 70 years) maintain a rate of cardiac events below 1%.

Material and methods:

554 patients were studied through gated-SPECT, divided into two groups: Group 1: (n = 354) with normal gated-SPECT, and Group 2: (n = 200) with abnormal gated-SPECT. We define a normal gated-SPECT as that with a stress sum score (SSS) <4 and normal functional parameters. The mean follow-up was 30.6 months (range: 12-62 months), for the investigation of cardiovascular events (CE): cardiac death (CD) and nonfatal infarction (NFAMI), and combined events (CBE): CE + coronary angioplasty, myocardial revascularization surgery and implanted cardiodefibrillator (ICD). Pearson’s nonparametric test was used and the Χ2 statistic was calculated, with a value of p <0.05 for the rejection of the null hypothesis (CI: 95%).


the comparison between both groups shows differences for the appearance of CE: (p <0.0001), CD: (p <0.0001) and CBE: (p <0.0001). The CE rate in Group 1 for each year was 0.56, 0.59 and 0.50%, respectively, with a cumulative 3-year rate of 1.65%. The rate in Group 2 was 2.5, 1.58 and 3.84%, respectively (cumulative rate: 7.92%). The period in which Group 1 patients maintained a risk of CD below 1% was 18 months.


the prognosis of elderly patients presenting a normal gated-SPECT result is very good, with a cardiac event rate of less than 1% for a period of 18 months.

Keywords : Cardiac gated single photon emission computer assisted tomography; Prognosis; Aged.

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