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Revista Uruguaya de Cardiología

On-line version ISSN 1688-0420


NARBONDO, Fabiana et al. Cardiodesfibriladores implantables: Diecinueve años de experiencia en un centro de nuestro país. Rev.Urug.Cardiol. [online]. 2013, vol.28, n.2, pp.141-150. ISSN 1688-0420.

Introduction: Implantable cardioverter defibrillator (ICD) has been reported to improve survival in patients at risk for sudden cardiac death (SCD). There is little follow up data in patients with ICD implant in Uruguay, although it has been used for 19 years already. Methods: A prospective observational cohort of 182 patients with first ICD implant was enrolled between February/1993 and June/2011. The follow up period was closed on 31/06/2012. Clinical characteristics: average age 57 ± 14 years, 83% men, 37% with left ventricular ejection fraction < 30%, coronary artery disease: 51% and secondary prevention ICD implant: 73%. Death, device replacement and first event were considered as end points. Survival curves were calculated by the Kaplan-Meier method (KM), using the SPSS V17.0. Incidence rates of first events were calculated in person-year-1 (IC95%) according to the ICD recorded therapies. Results: Overall survival: after a follow up of 988 years-patient (median: 4 years), the cumulative probability of survival (KM, IC95%) was 30% (% 5-55%). Device’s life time: after a follow up of 619 years-patient (median: 3,7 years) the cumulative probability of replacement (KM, IC95%) was 2,4% (2-7%). Events free survival: after a follow up of 428 years-patient (median: 1,3 years), the cumulative probability of events free survival (KM, IC95%) was 10% (1-19%). The incidence rate of appropriate shocks and antitachycardia therapy was 0,20 (0,16-0,24) and the inappropriate one was 0,07 (0,04-0,10). Conclusion: An acceptable probability of patients survival and device’s life time as well as an acceptable events free survival were observed in this cohort over a long follow up period


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