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Revista Uruguaya de Cardiología

On-line version ISSN 1688-0420

Abstract

BIA, DANIEL et al. Estudio integral no invasivo de la estructura y función arterial: Discusión de aspectos teóricos y prácticos del abordaje implementado en CUiiDARTE (Centro Universitario de Investigación, Innovación y Diagnóstico Arterial). Rev.Urug.Cardiol. [online]. 2010, vol.25, n.2, pp.105-138. ISSN 1688-0420.

Summary Traditional risk factors-guided cardiovascular prevention/treatment has clear limitations in individual subjects management. Often, individuals with similar risk factor profiles have differences in the atherosclerosis development and are at different cardiovascular risk. Therefore, while risk factors are good predictors of atherosclerosis in a population, they cannot identify who will develop the disease and/or will have a cardiovascular event. In this context, there have been published guidelines calling for non-invasive atherosclerosis screening and risk stratification in asymptomatic subjects. Several approaches have been proposed for the vascular evaluation, and although the screening tests used vary among laboratories, in general terms their are underused. In Uruguay, it was recently created an interdisciplinary university center (CUiiDARTE, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial), which has as a main aim the implementation of non-invasive techniques to evaluate the arterial structural and functional properties, that could allow stratifying the individual cardiovascular risk and identifying sub-clinical atherosclerosis. In this work we present the integral vascular approach used in CUiiDARTE and based in our experience we discuss, theoretical and practical issues related with the tests performed and parameters calculated.

Keywords : ANKLE-BRACHIAL INDEX;     ARTERIAL STIFFNESS; ATHEROSCLEROSIS; INTIMA-MEDIA THICKNESS; ENDOTHELIAL FUNCTION;     NON-INVASIVE STUDIES; ATHEROSCLEROTIC PLAQUE.

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