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Revista Uruguaya de Cardiología

versión On-line ISSN 1688-0420

Resumen

KORYTNICKI, DANIELA et al. Tiempo de reperfusión y mortalidad a cinco años en angioplastia primaria. Rev.Urug.Cardiol. [online]. 2008, vol.23, n.2, pp.142-149. ISSN 1688-0420.

SUMMARY Background: the benefit of pharmacological reperfusion in acute myocardial infarction has a strong dependence on time between beginning of symptoms and treatment. In primary angioplasty this relationship is not clear. Objective: to describe long term survival of patients treated with primary angioplasty depending on time to reperfusion of culprit vessel. Methods: all patients submitted to primary angioplasty from January 1999 to October 2002 were included. They were divided in four groups according to time to reperfusion 2 hours, 2 to 6 hours, more than 6 hours and without a well-known time period. Data were analyzed by Kaplan-Meier and log-rank test for survival curves. Results: 493 patients with primary angioplasty were tested with a 7,1% in hospital mortality. 137 patients (32%) were in the first group, 161(38%) in the second group, 58 (13,8%) and 70 patients (16,4%) in the third and fourth groups respectively. Mean follow-up time was 32 months. Patients who were treated after two hours were older, a higher percentage were women, more prevalent Killip III-IV classes and higher percentage of type C coronary lesions. The percentages of TIMI 3 flows were: 94,2%; 90,1%; 87,9% and 84,1% for groups 1,2 3 and 4 respectively. Patients treated in less than two hours had better survival (90,5%) than the rest of the groups (80,7%; 79,3% and 85,7% respectively). Conclusions: it seems to exist a relationship between a lesser time of myocardial infarction evolution and the moment of primary angioplasty and better long term survival, although it can not be discarded the possibility that this fact could be related to the characteristics of the selected population

Palabras clave : COHORT; PRIMARY ANGIOPLASTY; TIME TO REPERFUSION; LONG TERM SURVIVAL.

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