Abstract

GODOY, Mateo; PAPA, Patricia  and  DI PIETRO, Lucía. Long-acting octreotide and its use in malignant intestinal obstruction. Rev. Méd. Urug. [online]. 2026, vol.42, n.1, e704.  Epub Feb 12, 2026. ISSN 0303-3295.  https://doi.org/10.29193/rmu.42.1.15.

Malignant intestinal obstruction is a complex condition that poses a challenge for palliative care teams. Its symptoms have a physical and emotional impact on the patient, as well as on their environment. Rapid deterioration is usually associated with a poor prognosis of the disease. We present a case report of a 41-year-old patient with malignant small bowel obstruction, whose management was led by the Palliative Care team. During the course of the clinical condition, different drugs were used, including analgesics, steroids, gastrointestinal motility–promoting agents, and antisecretory agents. The use of somatostatin analogues, both immediate- and long-acting, is highlighted, achieving symptom remission that allowed clinical stabilisation for the 25 days following their administration, until the patient’s death.

Keywords : Malignant obstruction; Palliative care; Somatostatin analogues.

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