Abstract

ARIAS, Juan  and  AGUERO, Patricia. Men with hypogonadism secondary to macroprolactinoma. Rev. Méd. Urug. [online]. 2023, vol.39, n.1, e705.  Epub Mar 01, 2023. ISSN 0303-3295.  https://doi.org/10.29193/rmu.39.1.14.

Prolactinomas are the most common functioning pituitary tumors. According to size, they are classified into microprolactinomas (smaller than 1 cm) and macroprolactinomas (larger than or equal to 1 cm). The latter are more frequent among men and in general of late diagnosis upon compressive symptoms. Hyperprolactinemia interferes with the pulsatile secretion of the gonadotrophin releasing hormone (GnRH)) what results in inhibition of the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), what consequently produces hypogonadotrophic hypogonadism.

The study reports the clinical case of a 26-year-old male who was diagnosed with hypogonadotrophic hypogonadism secondary to macroprolactinoma, within the context of detained puberty.

Keywords : Hypogonadism; Prolactinoma; Macroprolactinoma; Hyperprolactinemia; Delayed puberty.

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