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Revista Médica del Uruguay

Print version ISSN 0303-3295On-line version ISSN 1688-0390


TARIGO, Josefina et al. Anal cytology screening in women with premalignant lesions of the uterine cervix. Rev. Méd. Urug. [online]. 2023, vol.39, n.1, e207.  Epub Mar 01, 2023. ISSN 0303-3295.


the main objective of the study was to assess the prevalence of anal cytology in women with a history of cervical intraepithelial neoplasia.


cohort transversal study conducted from May, 2018 until August, 2020 at Pereira Rossell Hospital. Two cohorts were studied, one of which included women with a diagnosis of cervical intraepithelial neoplasia and the other one included healthy women who attended their routine follow up, in a 2:1 ratio. The total size of the sample was 205 patients, 135 of which were patients with cervical intraepithelial neoplasia (confidence interval being 95%), presuming a 10% prevalence of anal pre-neoplasic lesions. The sample size of the control cohort was 70 patients as per the pre-defined ratio.


a association was found between the presence of malignant lesions of the cervix and epithelial anomalies detected in the anal cytology, with a prevalence coefficient of 1.77 (CI: 95%: 1,19 - 2,62) and odds ratio of 2,69 (1,36 - 5,30). No significant differences were found between race, type of sexual relationships or smoking variables.


our study concludes there is an association between cervical intraepithelial neoplasia related to HPV and pathological anal screening.

Keywords : Screening; Anal cytology; Cervical intraepithelial neoplasia; Human papilloma virus.

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